Crystal structures reveal a novel dimer of the RWD domain of human general control nonderepressible 2.
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DOI: 10.1016/j.bbrc.2021.02.111
Abstract: General control nonderepressible 2 (GCN2) is a serine/threonine protein kinase, detecting a variety of stresses including amino acid starvation, reactive oxygen species, etc. in eukaryotic cells. Activation of GCN2 requires the interaction of the N-terminal… read more here.
Keywords: dimer; crystal structures; rwd domain; domain ... See more keywords