Novel CTRP8-RXFP1-JAK3-STAT3 axis promotes Cdc42-dependent actin remodeling for enhanced filopodia formation and motility in human glioblastoma cells.
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DOI: 10.1002/1878-0261.12981
Abstract: CTRP8 is the least studied member of the C1Q-TNF related peptide family. We identified CTRP8 as a ligand of the G protein coupled receptor RXFP1 in glioblastoma multiforme (GBM). The CTRP8-RXFP1 ligand-receptor system protects human… read more here.
Keywords: rxfp1; stat3; rxfp1 jak3; jak3 stat3 ... See more keywords