Increased RyR2 activity is exacerbated by calcium leak-induced mitochondrial ROS
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DOI: 10.1007/s00395-020-0797-z
Abstract: Cardiac disease is associated with deleterious emission of mitochondrial reactive oxygen species (mito-ROS), as well as enhanced oxidation and activity of the sarcoplasmic reticulum (SR) Ca 2+ release channel, the ryanodine receptor (RyR2). The transfer… read more here.
Keywords: mitochondrial ros; ryr2; ros emission; activity ... See more keywords