FLIM‐FRET‐based analysis of S100A11/annexin interactions in living cells
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DOI: 10.1002/2211-5463.13782
Abstract: Proteins achieve their biological functions in cells by cooperation in protein complexes. In this study, we employed fluorescence lifetime imaging microscopy (FLIM)‐based Förster resonance energy transfer (FRET) measurements to investigate protein complexes comprising S100A11 and… read more here.
Keywords: based analysis; s100a11; cells flim; living cells ... See more keywords
Analysis of S100A11 in DNA Damage Repair.
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DOI: 10.1007/978-1-4939-9030-6_28
Abstract: DNA damage possesses the capacity to threaten the genomic integrity of an organism. A multitude of proteins are involved in the detection and repair of DNA double-strand breaks (DSBs), a severe kind of DNA damage.… read more here.
Keywords: dna damage; dna repair; dna; s100a11 ... See more keywords
S100A11/ANXA2 belongs to a tumour suppressor/oncogene network deregulated early with steatosis and involved in inflammation and hepatocellular carcinoma development
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DOI: 10.1136/gutjnl-2019-319019
Abstract: Objective Hepatocellular carcinoma (HCC) development occurs with non-alcoholic fatty liver disease (NAFLD) in the absence of cirrhosis and with an increasing incidence due to the obesity pandemic. Mutations of tumour suppressor (TS) genes and oncogenes… read more here.
Keywords: hepatocellular carcinoma; hcc; tumour suppressor; s100a11 ... See more keywords
Dual effects of targeting S100A11 on suppressing cellular metastatic properties and sensitizing drug response in gastric cancer
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DOI: 10.1186/s12935-021-01949-1
Abstract: Background S100A11 is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs. The dysregulated expression of the S100A11 gene has been implicated in tumour metastasis. However, the role of S100A11 protein… read more here.
Keywords: metastatic properties; response; gastric cancer; s100a11 ... See more keywords
The resealing factor S100A11 interacts with annexins and extended synaptotagmin-1 in the course of plasma membrane wound repair
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DOI: 10.3389/fcell.2022.968164
Abstract: After damage, cells repair their plasma membrane in an active process that is driven by Ca2+ entering through the wound. This triggers a range of Ca2+-regulated events such as the translocation of different Ca2+-binding proteins… read more here.
Keywords: membrane wound; wound repair; membrane; s100a11 ... See more keywords