Transcriptional activation of S100A2 expression by HIF‐1α via binding to the hypomethylated hypoxia response elements in HCC cells
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DOI: 10.1002/mc.23393
Abstract: Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal cancers. Dysregulation of S100A2 has recently been found in many cancers including HCC. However, its regulatory mechanism in HCC remains poorly understood, especially in… read more here.
Keywords: s100a2; hypoxia response; response elements; hcc ... See more keywords
S100A2 Silencing Relieves Epithelial-Mesenchymal Transition in Pulmonary Fibrosis by Inhibiting the Wnt/β-Catenin Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2020 at "DNA and cell biology"
DOI: 10.1089/dna.2020.6030
Abstract: Pulmonary fibrosis (PF) is a progressive and lethal disease with poor prognosis. S100A2 plays an important role in the progression of cancer. However, the role of S100A2 in PF has not yet been reported. In… read more here.
Keywords: mesenchymal transition; catenin signaling; epithelial mesenchymal; pulmonary fibrosis ... See more keywords
Expression Profile of S100A2 and its Clinicopathological Significance in Renal Cell Carcinoma
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DOI: 10.21873/anticanres.14654
Abstract: Background/Aim: Dysregulated expression of S100 protein family members, including S100A2, has been reported in various types of human malignant tumors; however, the functional role of S100A2 in renal cell carcinoma (RCC) remains unknown. The objective… read more here.
Keywords: renal cell; cell carcinoma; rcc; expression ... See more keywords
Influence of S100A2 in Human Diseases
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DOI: 10.3390/diagnostics12071756
Abstract: S100 proteins are a family of low-molecular-weight proteins characterized by two calcium-binding sites with a helix-loop-helix (“EF-hand-type”) domain. The S100 family of proteins is distributed across various organs and can interact with diverse molecules. Among… read more here.
Keywords: s100a2; family; s100a2 human; influence s100a2 ... See more keywords