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Published in 2018 at "Inflammation Research"
DOI: 10.1007/s00011-018-1147-6
Abstract: The pathophysiology of psoriasis is very complex and involves an interplay between immune cells and keratinocytes. The keratinocyte production of calprotectin (S100A8/A9), induced by the inflammatory psoriatic milieu, may be involved in initiating immune cell…
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Keywords:
biological therapy;
psoriatic patients;
s100a8;
expression ... See more keywords
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Published in 2019 at "Cytokine"
DOI: 10.1016/j.cyto.2018.11.033
Abstract: Background: Toll‐like receptors (TLR) 1 to 4 are highly expressed in aorta. Activation of TLR4 causes transmural arteritis in Human temporal artery‐SCID chimera model. Neither TLR‐4 nor its ligands have been studied in TA patients…
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Keywords:
blood mononuclear;
healthy controls;
s100a8;
peripheral blood ... See more keywords
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Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2018.12.008
Abstract: Activation of the inflammatory signaling pathway is the most vital part of the pre-metastatic events of breast cancer. Platycodin D (PlaD) shows favorable pharmacological activities in anti-inflammatory and anti-tumor effect. The main purpose of this…
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Keywords:
carcinoma 4t1;
4t1 cells;
s100a8 induced;
mammary carcinoma ... See more keywords
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Published in 2017 at "Immunology and Cell Biology"
DOI: 10.1038/icb.2017.2
Abstract: S100A8 and S100A9 are myeloid cell‐derived proteins that are elevated in several types of inflammatory lung disorders. Pro‐ and anti‐inflammatory properties are reported and these proteins are proposed to activate TLR4. S100A8 and S100A9 can…
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Keywords:
lung injury;
s100a8;
s100a9;
acute lung ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-17586-6
Abstract: Psychological stress is thought to be an important trigger of cardiovascular events, yet the involved pathways and mediators are largely unknown. Elevated systemic levels of the pro-inflammatory alarmin S100A8/A9 correlate with poor prognosis in coronary…
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Keywords:
response;
coronary artery;
s100a8;
stress ... See more keywords
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Published in 2023 at "Clinical transplantation"
DOI: 10.1111/ctr.15006
Abstract: OBJECTIVES S100A8/A9 is a damage-associated molecule that augments systemic inflammation. However, its role in the acute phase after lung transplantation (LTx) remains elusive. This study aimed to determine S100A8/A9 levels after lung transplantation (LTx) and…
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Keywords:
lung transplantation;
s100a8;
s100a8 levels;
survival ... See more keywords
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Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.2669
Abstract: Background Familial Mediterranean Fever (FMF) is caused by mutations in MEFV. The protein product pyrin is expressed in monocytes, neutrophils and eosinophils. Acute inflammatory attacks are accompanied by a dramatic hepatic acute phase response. S100A8/A9…
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Keywords:
serum s100a8;
none declared;
disease;
s100a8 ... See more keywords
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Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/6947652
Abstract: Background S100 Calcium Binding Protein A8 (S100A8) is beneficial for cancer immunotherapy. However, the processes underlying its therapeutic potential have not been completely studied. Methods The Cancer Genome Atlas provides raw data on 33 different…
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Keywords:
biomarker;
s100a8;
cancer immunotherapy;
tumor ... See more keywords
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Published in 2018 at "Journal of Dental Research"
DOI: 10.1177/0022034518756330
Abstract: Calprotectin (S100A8/A9), a heterodimeric complex of calcium-binding proteins S100A8 and S100A9, is encoded by genes mapping to the chromosomal locus 1q21.3 of the epidermal differentiation complex. Whereas extracellular calprotectin shows proinflammatory and antimicrobial properties by…
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Keywords:
head neck;
cell;
calprotectin;
s100a8 ... See more keywords
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Published in 2022 at "Experimental Biology and Medicine"
DOI: 10.1177/15353702221091990
Abstract: Severe coronavirus (SARS-COV-2) infection often leads to systemic inflammation accompanied by cardiovascular complications including venous thromboembolism (VTE). However, it is largely undefined if inflammatory markers such as lipocalin-2 (LNC2), calprotectin (S100A8/A9), and cystatin C (CST3),…
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Keywords:
predictive biomarkers;
s100a8;
s100a8 cystatin;
s100a8 cst3 ... See more keywords
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Published in 2022 at "Blood"
DOI: 10.1182/blood.2021014966
Abstract: Abstract S100A8/A9, also known as “calprotectin” or “MRP8/14,” is an alarmin primarily secreted by activated myeloid cells with antimicrobial, proinflammatory, and prothrombotic properties. Increased plasma levels of S100A8/A9 in thrombo-inflammatory diseases are associated with thrombotic…
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Keywords:
s100a8 drives;
s100a8;
procoagulant platelets;
gpib ... See more keywords