Circulating S100A8 and S100A9 protein levels in plasma of patients with acquired aplastic anemia and myelodysplastic syndromes
Sign Up to like & getrecommendations! Published in 2019 at "Cytokine"
DOI: 10.1016/j.cyto.2018.06.025
Abstract: &NA; The alarmin family members S100A8 and S100A9 are acute phase inflammation proteins, but they also have been proposed as biomarkers in many malignant and non‐malignant diseases. In this study, circulating S100A8 and S100A9 homodimers… read more here.
Keywords: circulating s100a8; aplastic anemia; protein levels; s100a8 s100a9 ... See more keywords
Expression of calcium-binding proteins S100A8, S100A9 and S100A12 in otitis media.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pediatric otorhinolaryngology"
DOI: 10.1016/j.ijporl.2017.07.025
Abstract: OBJECTIVES Calgranulins (calcium-binding proteins S100A8, S100A9 and S100A12) are predominant cytoplasmic proteins of neutrophils and produced by various cells, playing multiple functions in innate immunity and the inflammatory process. Although up-regulated expression of S100A8 and… read more here.
Keywords: s100a9 s100a12; expression; middle ear; gene ... See more keywords
S100A8/A9 and S100A9 reduce acute lung injury
Sign Up to like & getrecommendations! Published in 2017 at "Immunology and Cell Biology"
DOI: 10.1038/icb.2017.2
Abstract: S100A8 and S100A9 are myeloid cell‐derived proteins that are elevated in several types of inflammatory lung disorders. Pro‐ and anti‐inflammatory properties are reported and these proteins are proposed to activate TLR4. S100A8 and S100A9 can… read more here.
Keywords: lung injury; s100a8; s100a9; acute lung ... See more keywords
Transcriptome profiling of mouse colonic eosinophils reveals a key role for eosinophils in the induction of s100a8 and s100a9 in mucosal healing
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-07738-z
Abstract: Eosinophils are bone marrow-derived cells that have been largely implicated in Th2-associated diseases. Recent data highlights a key role for eosinophils in mucosal innate immune responses especially in the gastrointestinal (GI) tract, which is one… read more here.
Keywords: colonic eosinophils; mucosal healing; role eosinophils; key role ... See more keywords
RNA sequencing for ligature induced periodontitis in mice revealed important role of S100A8 and S100A9 for periodontal destruction
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-50959-7
Abstract: Periodontitis is an inflammatory disease caused by pathogenic oral microorganisms that induce the destruction of periodontal tissue. We sought to identify the relevant differentially expressed genes (DEGs) and clarify the mechanism underlying the rapid alveolar… read more here.
Keywords: destruction; s100a8 s100a9; ligature induced; induced periodontitis ... See more keywords
High plasma level of S100A8/S100A9 and S100A12 at admission indicates a higher risk of death in septic shock patients
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-52184-8
Abstract: Biomarkers in sepsis for severity, prediction of outcome or reversibility of organ dysfunction are warranted. Measurements of plasma DAMP levels at admission can reflect the severity of cellular damage in septic shock, which might predict… read more here.
Keywords: risk; septic shock; s100a9 s100a12; s100a8 s100a9 ... See more keywords
S100A8 and S100A9, biomarkers of SARS-CoV-2-infection and other diseases, suppress HIV replication in primary macrophages.
Sign Up to like & getrecommendations! Published in 2022 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2021.0193
Abstract: S100A8 and S100A9 are members of the Alarmin family; these proteins are abundantly expressed in neutrophils and form a heterodimer complex and secreted in plasma upon pathogen infection or acute inflammatory diseases. Recently, both proteins… read more here.
Keywords: s100a8 s100a9; infection; sars cov; cov infection ... See more keywords
Calcium-binding proteins S100A8, S100A9, and S100A12: expression and regulation at the maternal-conceptus Interface in pigs†.
Sign Up to like & getrecommendations! Published in 2022 at "Biology of reproduction"
DOI: 10.1093/biolre/ioac039
Abstract: Among the many calcium-binding proteins, S100A8, S100A9, and S100A12 play important roles in inflammation, innate immunity, and antimicrobial function, but their expression, regulation, and function at the maternal-conceptus interface in pigs are not fully understood.… read more here.
Keywords: s100a8 s100a9; conceptus; expression; s100a9 s100a12 ... See more keywords
Abstract 2956: Chemical library screen identifies compounds that target S100A8/S100A9 complex and MDSC accumulation
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-2956
Abstract: We previously demonstrated that MDSC subsets accumulated in primary tumor and distant organs regulate tumor plasticity. The mouse transcriptome analysis of in vitro co-cultures and samples from syngeneic mouse model revealed that granulocytic subset of… read more here.
Keywords: cancer; tumor; mdsc accumulation; s100a8 s100a9 ... See more keywords
S100A8 and S100A9 Promote Apoptosis of Chronic Eosinophilic Leukemia Cells
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01258
Abstract: S100A8 and S100A9 function as essential factors in inflammation and also exert antitumor or tumorigenic activity depending on the type of cancer. Chronic eosinophilic leukemia (CEL) is a rare hematological malignancy having elevated levels of… read more here.
Keywords: apoptosis; chronic eosinophilic; eosinophilic leukemia; s100a8 s100a9 ... See more keywords
Neutrophil Infiltration Characterized by Upregulation of S100A8, S100A9, S100A12 and CXCR2 Is Associated With the Co-Occurrence of Crohn’s Disease and Peripheral Artery Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.896645
Abstract: Background Crohn’s disease (CD) and peripheral arterial disease (PAD) are closely related. The pathophysiological mechanisms underlying the coexistence of CD and PAD are unknown. The aim of this study was to investigate the key molecules… read more here.
Keywords: hub genes; s100a8 s100a9; s100a9 s100a12; s100a12 cxcr2 ... See more keywords