The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex.
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DOI: 10.1016/j.jphs.2017.07.001
Abstract: S14161 is a pan-Class I PI3K inhibitor that induces blood cancer cell death, but its mechanism is largely unknown. In the present study, we evaluated the role of S14161 in autophagy, an emerging event in… read more here.
Keywords: s14161; pi3k inhibitor; beclin; class pi3k ... See more keywords