Articles with "s1r antagonists" as a keyword



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Comprehensive 3D-QSAR Model Predicts Binding Affinity of Structurally Diverse Sigma 1 Receptor Ligands

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Published in 2019 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.8b00521

Abstract: The Sigma 1 Receptor (S1R) has attracted intense interest as a pharmaceutical target for various therapeutic indications, including the treatment of neuropathic pain and the potentiation of opioid analgesia. Efforts by drug developers to rationally… read more here.

Keywords: s1r antagonists; qsar model; structurally diverse; model ... See more keywords