Development of a Novel σ1 Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells.
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DOI: 10.1021/acschemneuro.3c00206
Abstract: The σ1 receptor (S1R) is a ligand-regulated non-opioid intracellular receptor involved in several pathological conditions. The development of S1R-based drugs as therapeutic agents is a challenge due to the lack of simple functional assays to… read more here.
Keywords: s1r; heterodimerization; binding immunoglobulin; s1r bip ... See more keywords