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Four Molybdenum-Dependent Steroid C-25 Hydroxylases: Heterologous Overproduction, Role in Steroid Degradation, and Application for 25-Hydroxyvitamin D3 Synthesis

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Published in 2018 at "mBio"

DOI: 10.1128/mbio.00694-18

Abstract: ABSTRACT Side chain-containing steroids are ubiquitous constituents of biological membranes that are persistent to biodegradation. Aerobic, steroid-degrading bacteria employ oxygenases for isoprenoid side chain and tetracyclic steran ring cleavage. In contrast, a Mo-containing steroid C-25… read more here.

Keywords: degradation; steroid degradation; molybdenum dependent; dependent steroid ... See more keywords