Articles with "s34f mutation" as a keyword



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Ribosome biogenesis is a downstream effector of the oncogenic U2AF1-S34F mutation

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Published in 2020 at "PLoS Biology"

DOI: 10.1371/journal.pbio.3000920

Abstract: U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1) forms a heterodimeric complex with U2AF2 that is primarily responsible for 3สน splice site selection. U2AF1 mutations have been identified in most cancers but are prevalent in… read more here.

Keywords: u2af1 s34f; s34f mutation; mutation; ribosome biogenesis ... See more keywords