Articles with "s49076" as a keyword



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First-in-human phase I study of oral S49076, a unique MET/AXL/FGFR inhibitor, in advanced solid tumours.

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Published in 2017 at "European journal of cancer"

DOI: 10.1016/j.ejca.2017.05.007

Abstract: BACKGROUND AND OBJECTIVES S49076 is a novel ATP-competitive tyrosine kinase inhibitor of MET, AXL and FGFR with a unique selectivity profile. A phase I open-label study was undertaken to establish the tolerability profile and determine… read more here.

Keywords: phase; axl fgfr; advanced solid; s49076 ... See more keywords