Articles with "s63845" as a keyword



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Sensitivity of Cutaneous T-Cell Lymphoma Cells to the Mcl-1 Inhibitor S63845 Correlates with the Lack of Bcl-w Expression

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232012471

Abstract: Long-term, curative treatment of cutaneous T-cell lymphomas (CTCL) remains a major challenge. Therapy resistance is often based on apoptosis deficiency, and may depend on antiapoptotic Bcl-2 proteins, such as Bcl-2, Bcl-xL, Bcl-w and Mcl-1. For… read more here.

Keywords: cell; bcl bcl; expression; s63845 ... See more keywords