Consolidative Radiotherapy for Limited Metastatic Non–Small-Cell Lung Cancer: A Phase 2 Randomized Clinical Trial
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.3501
Abstract: Importance Patterns-of-failure studies suggest that in metastatic non–small-cell lung cancer (NSCLC) sites of gross disease at presentation are the first to progress when treated with chemotherapy. This knowledge has led to increased adoption of local… read more here.
Keywords: chemotherapy; disease; maintenance chemotherapy; sabr ... See more keywords
Treatment With Stereotactic Ablative Radiotherapy for Up to 5 Oligometastases in Patients With Cancer: Primary Toxic Effect Results of the Nonrandomized Phase 2 SABR-5 Clinical Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.4394
Abstract: Importance After the publication of the landmark SABR-COMET trial, concerns arose regarding high-grade toxic effects of treatment with stereotactic ablative body radiotherapy (SABR) for oligometastases. Objective To document toxic effects of treatment with SABR in… read more here.
Keywords: sabr; trial; phase; toxic effects ... See more keywords
Stereotactic Ablative radiotherapy before resection to avoid delay for early-stage lung cancer or oligometastases during the COVID-19 pandemic: Pathologic outcomes from the SABR-BRIDGE protocol.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer"
DOI: 10.1002/cncr.34880
Abstract: BACKGROUND During coronavirus disease 2019 (COVID-19)-related operating room closures, some multidisciplinary thoracic oncology teams adopted a paradigm of stereotactic ablative radiotherapy (SABR) as a bridge to surgery, an approach called SABR-BRIDGE. This study presents the… read more here.
Keywords: sabr; sabr bridge; stereotactic ablative; ablative radiotherapy ... See more keywords
Volumetric modulated arc therapy (VMAT) comparison to 3D‐conformal technique in lung stereotactic ablative radiotherapy (SABR)
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DOI: 10.1002/jmrs.634
Abstract: Stereotactic ablative radiotherapy (SABR) can be a curative option for non‐small cell lung cancer (NSCLC) and oligometastatic lung disease. Volumetric modulated arc therapy (VMAT) has offered further advancements in terms of radiation dose shaping without… read more here.
Keywords: sabr; stereotactic ablative; ablative radiotherapy; radiotherapy ... See more keywords
Treatment completion, treatment compliance and outcomes of old and very old patients treated by dose adapted stereotactic ablative radiotherapy (SABR) for T1-T3N0M0 non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of geriatric oncology"
DOI: 10.1016/j.jgo.2018.10.011
Abstract: AIM This is a retrospective single-institution review of the treatment completion and clinical outcomes of patients aged 75 and older, treated with stereotactic ablative body radiotherapy (SABR) for T1-T3 N0 M0 non-small cell lung cancer (NSCLC). MATERIAL… read more here.
Keywords: old old; treatment; old patients; treatment completion ... See more keywords
SABR improves outcomes
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DOI: 10.1038/s41571-019-0217-1
Abstract: According to the oligometastatic paradigm, patients with a limited number of metastatic lesions can be amenable to curative treatment if all lesions are resected or ablated using stereotactic ablative radiotherapy (SABR). Most of the evidence… read more here.
Keywords: trial; treatment; sabr improves; improves outcomes ... See more keywords
Can dosimetry affect local control and survival in patients with early-stage lung cancer treated with Stereotactic Ablative Radiotherapy (SABR)? An analysis of the UK's largest cohort of lung SABR patients
Sign Up to like & getrecommendations! Published in 2021 at "Acta Oncologica"
DOI: 10.1080/0284186x.2021.1874617
Abstract: Abstract Purpose/objectives A recent study has shown that tight conformity of lung Stereotactic Ablative Radiotherapy (SABR) plans might worsen loco-regional control and can predict distant metastases. The study aims to report overall survival (OS), progression-free… read more here.
Keywords: lung; lung cancer; volume; sabr ... See more keywords
S101 A comparison of the imaging features of early stage primary lung cancer in patients treated with surgery, sabr and microwave ablation
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DOI: 10.1136/thoraxjnl-2017-210983.107
Abstract: Introduction Stereotactic Ablative Radiotherapy (SABR) and percutaneous microwave ablation (PMWA) are now being performed in patients deemed “medically inoperable” with non-small cell lung cancer (NSCLC). The majority of these patients are treated without ground truth… read more here.
Keywords: surg; lung cancer; malignancy; microwave ablation ... See more keywords
Population-based phase II trial of stereotactic ablative radiotherapy (SABR) for up to 5 oligometastases: SABR-5
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DOI: 10.1186/s12885-018-4859-7
Abstract: BackgroundOligometastases refer to a state of disease where cancer has spread beyond the primary site, but is not yet widely metastatic, often defined as 1–3 or 1–5 metastases in number. Stereotactic ablative radiotherapy (SABR) is… read more here.
Keywords: trial; population based; radiotherapy; toxicity ... See more keywords
Robotic stereotactic ablative radiotherapy for renal cell carcinoma in patients with impaired renal function
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DOI: 10.1186/s12894-019-0531-z
Abstract: BackgroundRobotic stereotactic ablative radiotherapy (SABR) is currently under investigation as a noninvasive treatment option for patients with renal cell carcinoma (RCC). For radiation therapy of RCC, tumor motion and the need for high ablative doses… read more here.
Keywords: motion; rcc; function; renal function ... See more keywords
Prevalence of oligoprogressive, metastatic castration-resistant prostate cancer (mCRPC) amenable to stereotactic ablative radiotherapy (SABR) in men undergoing abiraterone acetate (AA) therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.6_suppl.e587
Abstract: e587Background: SABR is increasingly used for the treatment of men with oligometastatic prostate cancer, including patients (pts) presenting with oligoprogression. The latter is a clinical situation where a limited number of metastatic tumor sites progress… read more here.
Keywords: therapy; sabr; prostate cancer; men undergoing ... See more keywords