Comparison of putative BH3 mimetics AT-101, HA14-1, sabutoclax and TW-37 with ABT-737 in platelets
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DOI: 10.1080/09537104.2020.1724276
Abstract: Abstract Platelet lifespan is regulated by intrinsic apoptosis. Platelet apoptosis can be triggered by BH3 mimetics that inhibit the pro-survival Bcl-2 family protein, Bcl-xL. Here, we investigated several small molecules that are reported to act… read more here.
Keywords: ha14; sabutoclax; abt 737; bh3 mimetics ... See more keywords