Identification of SaCas9 orthologs containing a conserved serine residue that determines simple NNGG PAM recognition
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DOI: 10.1371/journal.pbio.3001897
Abstract: Due to different nucleotide preferences at target sites, no single Cas9 is capable of editing all sequences. Thus, this highlights the need to establish a Cas9 repertoire covering all sequences for efficient genome editing. Cas9s… read more here.
Keywords: serine residue; sacas9 orthologs; nngg pam; simple nngg ... See more keywords