Full-Length Model of SaCas9-sgRNA-DNA Complex in Cleavage State
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DOI: 10.3390/ijms24021204
Abstract: Staphylococcus aureus Cas9 (SaCas9) is a widely used genome editing tool. Understanding its molecular mechanisms of DNA cleavage could effectively guide the engineering optimization of this system. Here, we determined the first cryo-electron microscopy structure… read more here.
Keywords: cleavage; sacas9 sgrna; sacas9; model ... See more keywords