Discovery of Presaccharothriolide X, a Retro-Michael Reaction Product of Saccharothriolide B, from the Rare Actinomycete Saccharothrix sp. A1506.
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DOI: 10.1021/acs.orglett.8b01535
Abstract: The highly reactive precursor molecule, presaccharothriolide X, was successfully isolated from the rare actinomycete Saccharothrix sp. A1506. The comparable biological activity of presaccharothriolide X and its Michael addition product saccharothriolide B unveils a unique masking/activating… read more here.
Keywords: rare actinomycete; saccharothrix a1506; retro michael; michael reaction ... See more keywords