The Natural History of a Patient with Sacral Chordoma: Case Report and Literature Review.
Sign Up to like & getrecommendations! Published in 2020 at "World neurosurgery"
DOI: 10.1016/j.wneu.2020.03.214
Abstract: Background Chordomas are rare, slow-growing, locally aggressive, malignant tumors of the spine. Chordomas are conventionally treated with surgical resection with or without radiation. There is an absence of literature documenting the natural history of a… read more here.
Keywords: literature; case; natural history; sacral chordoma ... See more keywords
Fingolimod inhibits proliferation and epithelialâmesenchymal transition in sacral chordoma by inactivating IL-6/STAT3 signalling
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DOI: 10.1042/bsr20200221
Abstract: Abstract Purpose: To explore the sensitivity of the immunosuppressive agent fingolimod (FTY720) in chordoma and determine whether it can serve as an appropriate alternate treatment for unresectable tumours in patients after incomplete surgery. Methods: Cell… read more here.
Keywords: stat3 signalling; chordoma; sacral chordoma; epithelial mesenchymal ... See more keywords
High-intensity focused ultrasonic ablation of sacral chordoma is feasible: a series of four cases and details of a national clinical trial
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Neurosurgery"
DOI: 10.1080/02688697.2016.1267330
Abstract: Abstract High-intensity focused ultrasound describes the use of high-intensity focused ultrasound (HIFU) to ablate tumours without requiring an incision or other invasive procedure. This technique has been trialled on a range of tumours including uterine… read more here.
Keywords: high intensity; trial; sacral chordoma; intensity focused ... See more keywords
Pelvic exenteration with high sacrectomy and reconstruction with 3Dâprinted prosthesis for recurrent sacral chordoma
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DOI: 10.1111/ans.17952
Abstract: A 74-year-old woman with a history of multiple resections and radiotherapy for recurrent sacral chordoma was referred with local recurrence, manifesting as symptoms of lower back pain, constipation and urinary incontinence. At baseline, she had… read more here.
Keywords: pelvic exenteration; high sacrectomy; recurrent sacral; sacral chordoma ... See more keywords
Outcomes of Surgery for Sacral Chordoma and Impact of Complications: A Report of 50 Consecutive Patients With Long-Term Follow-Up
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DOI: 10.1177/21925682211011444
Abstract: Study Design: Retrospective case series. Objective: To determine predictive factors of overall survival (OS) and local recurrence (LR), report complications, and assess the impact of complications on survival, recurrence, and function in patients undergoing en… read more here.
Keywords: multivariable cox; cox regression; sacral chordoma; impact complications ... See more keywords
Sacral Chordoma: A Population-based Analysis of Epidemiology and Survival Outcomes
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DOI: 10.21873/anticanres.15552
Abstract: Background/Aim: Sacral chordoma is a rare primary bone neoplasm associated with high morbidity. The aim of this study is to identify demographic and clinicopathological characteristics of this tumor and evaluate their impact on survival outcomes.… read more here.
Keywords: survival; epidemiology; overall survival; sacral chordoma ... See more keywords
Radiotherapy for Mobile Spine and Sacral Chordoma: A Critical Review and Practical Guide from the Spine Tumor Academy
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DOI: 10.3390/cancers15082359
Abstract: Simple Summary Chordomas are rare tumors of the embryologic spinal cord remnant. They are locally aggressive and typically managed with surgery in combination with radiation therapy. However, there is great variability in practice patterns including… read more here.
Keywords: chordoma; tumor academy; spine tumor; spine sacral ... See more keywords