Identification and epitope mapping of swine acute diarrhea syndrome coronavirus accessory protein NS7a via monoclonal antibodies
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DOI: 10.1016/j.virusres.2022.198742
Abstract: Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an emerging swine enteric coronavirus that causes vomiting, severe diarrhea, dehydration and death in suckling piglets. NS7a is putative accessory protein that is predicted to be encoded by… read more here.
Keywords: epitope; swine acute; sads cov; ns7a protein ... See more keywords
A Novel Reverse Transcription Droplet Digital PCR Assay for the Sensitive Detection of Combing Severe Acute Respiratory Syndrome Coronavirus 2 with Swine Acute Diarrhea Syndrome Coronavirus.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsac039
Abstract: BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread over the world since its emergence. Although the dominant route of SARS-CoV-2 infection is respiratory, a number of studies revealed infectious risk from contaminated… read more here.
Keywords: sads cov; syndrome coronavirus; sars cov; detection ... See more keywords
Retrospective detection and phylogenetic analysis of swine acute diarrhoea syndrome coronavirus in pigs in southern China
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DOI: 10.1111/tbed.13008
Abstract: Summary Swine acute diarrhoea syndrome coronavirus (SADS‐CoV), a novel coronavirus, was first discovered in southern China in January 2017 and caused a large scale outbreak of fatal diarrheal disease in piglets. Here, we conducted a… read more here.
Keywords: sads cov; syndrome coronavirus; swine acute; coronavirus ... See more keywords
The re‐emerging of SADS‐CoV infection in pig herds in Southern China
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DOI: 10.1111/tbed.13270
Abstract: Abstract A new highly virulent swine acute diarrhoea syndrome coronavirus (SADS‐CoV) emerged in Guangdong province in 2017 followed by fatal diarrhoea that involved the death of 24,693 piglets. And yet from May 2017 to January… read more here.
Keywords: emerging sads; sads cov; pig herds; southern china ... See more keywords
First evidence that an emerging mammalian alphacoronavirus is able to infect an avian species.
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DOI: 10.1111/tbed.14535
Abstract: A novel swine enteric alphacoronavirus, swine acute diarrhea syndrome coronavirus (SADS-CoV), related to Rhinolophus bat CoV HKU2 in the subgenus Rhinacovirus has emerged in southern China in 2017, causing diarrhea in newborn piglets, and critical… read more here.
Keywords: sads cov; alphacoronavirus able; infect avian; able infect ... See more keywords
Lethal Swine Acute Diarrhea Syndrome Coronavirus Infection in Suckling Mice
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DOI: 10.1128/jvi.00065-22
Abstract: SADS-CoV, which likely has originated from bat coronaviruses, is highly pathogenic to piglets and poses a threat to the swine industry. Little is known about its potential to disseminate to other animals. ABSTRACT Swine acute… read more here.
Keywords: sads cov; infection; coronavirus; swine acute ... See more keywords
Autophagy is induced by swine acute diarrhea syndrome coronavirus through the cellular IRE1-JNK-Beclin 1 signaling pathway after an interaction of viral membrane-associated papain-like protease and GRP78
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DOI: 10.1371/journal.ppat.1011201
Abstract: Autophagy plays an important role in the infectious processes of diverse pathogens. For instance, cellular autophagy could be harnessed by viruses to facilitate replication. However, it is still uncertain about the interplay of autophagy and… read more here.
Keywords: sads cov; signaling pathway; jnk beclin; beclin signaling ... See more keywords
Metabolomic analysis of porcine intestinal epithelial cells during swine acute diarrhea syndrome coronavirus infection
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DOI: 10.3389/fcimb.2022.1079297
Abstract: Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an enveloped, positive single-stranded RNA virus belonging to Coronaviridae family, Orthocoronavirinae subfamily, Alphacoronavirus genus. As one of the main causes of swine diarrhea, SADS-CoV has brought huge losses… read more here.
Keywords: sads cov; syndrome coronavirus; infection; swine acute ... See more keywords
A Comparative Analysis of Coronavirus Nucleocapsid (N) Proteins Reveals the SADS-CoV N Protein Antagonizes IFN-β Production by Inducing Ubiquitination of RIG-I
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DOI: 10.3389/fimmu.2021.688758
Abstract: Coronaviruses (CoVs) are a known global threat, and most recently the ongoing COVID-19 pandemic has claimed more than 2 million human lives. Delays and interference with IFN responses are closely associated with the severity of… read more here.
Keywords: protein; ubiquitination rig; comparative analysis; sads cov ... See more keywords
Analysis of Interaction Network Between Host Protein and M Protein of Swine Acute Diarrhea Syndrome Coronavirus
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DOI: 10.3389/fmicb.2022.858460
Abstract: Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an enterovirus that can cause acute diarrhea and death in piglets and cause serious economic losses to the pig industry. SADS-CoV membrane (M) protein mainly plays a key… read more here.
Keywords: sads cov; interaction; acute diarrhea; host ... See more keywords
Epitopes screening and vaccine molecular design of SADS-CoV based on immunoinformatics
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DOI: 10.3389/fvets.2022.1080927
Abstract: The regional outbreak of the Swine acute diarrhea syndrome coronavirus (SADS-CoV) has seriously threatened the swine industry. There is an urgent need to discover safe and effective vaccines to contain them quickly. The coronavirus spike… read more here.
Keywords: sads cov; epitope; design sads; epitopes screening ... See more keywords