Articles with "sae mice" as a keyword



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Probiotics Exert Protective Effect against Sepsis-Induced Cognitive Impairment by Reversing Gut Microbiota Abnormalities.

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Published in 2020 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.0c06332

Abstract: Recent evidence has revealed that probiotics could affect neurodevelopment and cognitive function via regulating gut microbiota. However, the role of probiotics in sepsis-associated encephalopathy (SAE) remained unclear. This study was conducted to assess the effects… read more here.

Keywords: sae mice; cognitive impairment; gut microbiota;
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Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice

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Published in 2023 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.1038802

Abstract: This study aimed to explore the protective roles of malvidin in life-threatened sepsis-associated encephalopathy (SAE) and illustrate the underlying mechanism. SAE mice models were developed and treated with malvidin for subsequently protective effects evaluation. Malvidin… read more here.

Keywords: sae; ros accumulation; mitochondrial dysfunction; sae mice ... See more keywords