Autoantibody to scaffold attachment factor B (SAFB): A novel connective tissue disease-related autoantibody associated with interstitial lung disease.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2016.09.006
Abstract: OBJECTIVE To identify and characterize a novel connective tissue disease (CTD)-related autoantibody (autoAb) directed against scaffold attachment factor B (SAFB). METHODS AutoAb specificity was analyzed using RNA and protein-immunoprecipitation assays. Autoimmune targets were affinity purified… read more here.
Keywords: autoantibody; safb; novel connective; connective tissue ... See more keywords
SAFB regulates hippocampal stem cell fate by targeting Drosha to destabilize Nfib mRNA
Sign Up to like & getrecommendations! Published in 2024 at "eLife"
DOI: 10.7554/elife.74940
Abstract: Neural stem cells (NSCs) are multipotent and correct fate determination is crucial to guarantee brain formation and homeostasis. How NSCs are instructed to generate neuronal or glial progeny is not well understood. Here, we addressed… read more here.
Keywords: nfib mrna; fate; safb; stem ... See more keywords