Engineered Macrophages: A Safe-by-Design Approach for the Tumor Targeting Delivery of Sub-5 nm Gold Nanoparticles.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202205474
Abstract: Ultrasmall nanoparticles (NPs) are a promising platform for the diagnosis and therapy of cancer, but the particles in sizes as small as several nanometers have an ability to translocate across biological barriers, which may bring… read more here.
Keywords: engineered macrophages; safe design; design approach; gold ... See more keywords
An Integrated Data-Driven Strategy for Safe-by-Design Nanoparticles: The FP7 MODERN Project.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-47754-1_9
Abstract: The development and implementation of safe-by-design strategies is key for the safe development of future generations of nanotechnology enabled products. The safety testing of the huge variety of nanomaterials that can be synthetized is unfeasible… read more here.
Keywords: project; data driven; safe design; integrated data ... See more keywords
Safe by Design for Nanomaterials—Late Lessons from Early Warnings for Sustainable Innovation
Sign Up to like & getrecommendations! Published in 2021 at "NanoEthics"
DOI: 10.1007/s11569-021-00393-9
Abstract: The Safe by Design conceptual initiative being developed for nanomaterials offers a template for a new sustainable innovation approach for advanced materials with four important sustainability characteristics. Firstly, it requires potential toxicity risks to be… read more here.
Keywords: sustainable innovation; innovation; safe design; design nanomaterials ... See more keywords
Safe Design of Consecutive-K-out-of-N Systems under Uncertainty
Sign Up to like & getrecommendations! Published in 2017 at "IFAC-PapersOnLine"
DOI: 10.1016/j.ifacol.2017.08.2307
Abstract: Abstract A linear (circular) consecutive-k-out-of-n: F (Con/k/n: F) system consists of n components that are linearly (circularly) arranged such that the system fails if and only if at least k consecutive components fail. The safe… read more here.
Keywords: system; design consecutive; uncertainty; safe design ... See more keywords
Integrative approach in a safe by design context combining risk, life cycle and socio-economic assessment for safer and sustainable nanomaterials
Sign Up to like & getrecommendations! Published in 2021 at "NanoImpact"
DOI: 10.1016/j.impact.2021.100335
Abstract: Abstract Moving towards safe and sustainable innovations is an international policy ambition. In the on-hand manuscript, a concept combining safe by design and sustainability was implemented through the integration of human and environmental risk assessment,… read more here.
Keywords: life cycle; safe design; design; risk ... See more keywords
24 Safe-by-Design Guidance for Multicomponent Nanostructured Materials (MCNM): Heavy Metals Containing Perovskites
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Work Exposures and Health"
DOI: 10.1093/annweh/wxac087.111
Abstract: Industry develops increasingly complex and advanced materials while incorporating the Safe-by-Design (SbD) concept into the R&D goals. Within HARMLESS (EU H2020), we use concepts of similarity for the risk screening during the SbD iterations. We… read more here.
Keywords: design guidance; safe design; heavy metals; materials mcnm ... See more keywords
47 Safe-by-Design Advanced Materials: A case Study on Paint Formulation
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Work Exposures and Health"
DOI: 10.1093/annweh/wxac087.123
Abstract: Paint formulations are complex mixtures of both dissolved and particulate components, both organic and inorganic. Amorphous silica nanoparticles are included to make the paint layer dirt-repellent. Over entire life cycle of the paints containing such… read more here.
Keywords: case study; paint; safe design; silica nanoparticles ... See more keywords
Identification of the safe(r) by design alternatives for nanosilver-enabled wound dressings
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.987650
Abstract: The use of silver nanoparticles (NPs) in medical devices is constantly increasing due to their excellent antimicrobial properties. In wound dressings, Ag NPs are commonly added in large excess to exert a long-term and constant… read more here.
Keywords: safe design; medical devices; identification safe; wound dressings ... See more keywords
A Safe-by-Design Approach to “Reef Safe” Sunscreens Based on ZnO and Organic UV Filters
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11112209
Abstract: In recent years, the issue of coral bleaching has led to restrictions in some tropical locations (i.e., Palau, Hawaii, etc.) on the use of some organic UV sunscreen filters, such as oxybenzone and ethyl hexyl… read more here.
Keywords: safe design; organic filters; zno organic; design approach ... See more keywords
Adopting Safe-by-Design in Science and Engineering Academia: The Soil May Need Tilling
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19042075
Abstract: In recent years, Safe-by-Design (SbD) has been launched as a concept that supports science and engineering such that a broad conception of safety is embraced and structurally embedded. The present study explores the extent to… read more here.
Keywords: safety; science engineering; engineering; safe design ... See more keywords
The Role of Polymeric Coatings for a Safe-by-Design Development of Biomedical Gold Nanoparticles Assessed in Zebrafish Embryo
Sign Up to like & getrecommendations! Published in 2021 at "Nanomaterials"
DOI: 10.3390/nano11041004
Abstract: In the biomedical field, gold nanoparticles (GNPs) have attracted the attention of the scientific community thanks to their high potential in both diagnostic and therapeutic applications. The extensive use of GNPs led researchers to investigate… read more here.
Keywords: gold nanoparticles; safe design; gold; gnp ... See more keywords