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   Articles with "safety" as a keyword



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Safety and Efficacy of Antithrombotic Strategies in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A Network Meta-analysis of Randomized Controlled Trials.

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recommendations! Published in 2019 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2019.1880

Abstract: Importance The antithrombotic treatment of patients with atrial fibrillation (AF) and coronary artery disease, in particular with acute coronary syndrome (ACS) and/or percutaneous coronary intervention (PCI), poses a significant treatment dilemma in clinical practice. Objective… read more here.

Keywords: inhibitor; analysis; p2y12 inhibitor; safety ... See more keywords
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Efficacy and Safety of Dapagliflozin According to Background Use of Cardiovascular Medications in Patients With Type 2 Diabetes: A Prespecified Secondary Analysis of a Randomized Clinical Trial.

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recommendations! Published in 2022 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2022.2006

Abstract: Importance Dapagliflozin was shown to reduce the cardiovascular (CV) and kidney outcomes in patients with type 2 diabetes. However, data are limited on the relationship of the effect and safety with the concurrent use of… read more here.

Keywords: patients type; safety; kidney; type diabetes ... See more keywords
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Efficacy and Safety of Guselkumab, an Anti–interleukin 23 Monoclonal Antibody, for Palmoplantar Pustulosis: A Randomized Clinical Trial

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recommendations! Published in 2018 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2017.5937

Abstract: Importance Palmoplantar pustulosis (PPP) is a recalcitrant skin disease with no biologics currently approved for treatment. The involvement of interleukin 23 (IL-23) and cytokines of the type 17 helper T cell lineage in the pathogenesis… read more here.

Keywords: week; trial; safety; group ... See more keywords
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Assessment of the Safety Risk of Dermatoscope Magnets in Patients With Cardiovascular Implanted Electronic Devices

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recommendations! Published in 2018 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2018.2531

Abstract: Importance Cardiovascular implanted electronic devices (CIEDs) are susceptible to electromagnetic interference. Dermatologists regularly use devices containing magnets, including dermatoscopes and their attachments, which could pose a hazard to patients with CIEDs. Objective To investigate the… read more here.

Keywords: strength; dermatology; field; safety ... See more keywords
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Efficacy and Safety of Guselkumab in Japanese Patients With Palmoplantar Pustulosis: A Phase 3 Randomized Clinical Trial.

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recommendations! Published in 2019 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2019.1394

Abstract: Importance Palmoplantar pustulosis (PPP) causes erythematous, scaly plaques with recurrent sterile pustules refractory to treatment and with few randomized clinical trials conducted. Evidence points to involvement of interleukin 23 in the pathogenesis of PPP. Objective… read more here.

Keywords: dermatology; safety; group; randomized clinical ... See more keywords
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Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial.

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recommendations! Published in 2021 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2021.3023

Abstract: Importance Atopic dermatitis (AD) is a chronic, recurrent, inflammatory skin disease with an unmet need for treatments that provide rapid and high levels of skin clearance and itch improvement. Objective To assess the safety and… read more here.

Keywords: week; safety; efficacy; upadacitinib dupilumab ... See more keywords
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Bimekizumab Safety in Patients With Moderate to Severe Plaque Psoriasis

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recommendations! Published in 2022 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2022.1185

Abstract: Key Points Question What is the 2-year safety profile of bimekizumab in patients with moderate to severe plaque psoriasis? Findings In this cohort study including 1789 patients receiving bimekizumab, pooled data on 2 years of… read more here.

Keywords: safety; patients moderate; moderate severe; plaque psoriasis ... See more keywords
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Biosimilars for the Treatment of Psoriasis: A Systematic Review of Clinical Trials and Observational Studies.

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recommendations! Published in 2023 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2023.1338

Abstract: Importance Biosimilars have the potential to reduce costs for the management of moderate-to-severe psoriasis compared with originators. However, the extrapolation of evidence enables the approval of a biosimilar for use in indications held by the… read more here.

Keywords: safety; clinical trials; biosimilars treatment; evidence ... See more keywords
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Continued High Rates of IVC Filter Use After US Food and Drug Safety Warning.

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recommendations! Published in 2017 at "JAMA internal medicine"

DOI: 10.1001/jamainternmed.2017.2724

Abstract: Editor's Note Continued High Rates of IVC Filter Use After US Food and Drug Safety Warning Inferior vena cava (IVC) filters have drawn my attention since I learned about their serious risks from Nicholson and… read more here.

Keywords: filter use; use; ivc filters; safety ... See more keywords
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Probiotic Safety-No Guarantees.

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recommendations! Published in 2018 at "JAMA internal medicine"

DOI: 10.1001/jamainternmed.2018.5403

Abstract: For centuries, people have consumed live bacteria in many foods, such as yogurt, cheese, kimchi, and sauerkraut. The mass-marketing of isolated live bacteria for their purported beneficial or “probiotic” properties, however, is a relatively recent… read more here.

Keywords: probiotic supplements; safety; live microorganisms; resistance ... See more keywords
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Association Between Data Sources and US Food and Drug Administration Drug Safety Communications.

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recommendations! Published in 2019 at "JAMA internal medicine"

DOI: 10.1001/jamainternmed.2019.3066

Abstract: Association Between Data Sources and US Food and Drug Administration Drug Safety Communications Drug safety communications (DSCs) are the primary tool for the US Food and Drug Administration (FDA) to communicate important new postmarketing safety… read more here.

Keywords: safety communications; safety; drug administration; drug ... See more keywords