Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs
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DOI: 10.1007/s40265-020-01364-2
Abstract: The incidence of osteoporosis and cardiovascular disease increases with age, and there are potentially shared mechanistic associations between the two conditions. It is therefore highly relevant to understand the cardiovascular implications of osteoporosis medications. These… read more here.
Keywords: anti osteoporosis; assessment cardiovascular; safety anti; cardiovascular safety ... See more keywords
Efficacy and safety of anti-PD-1/PD-L1 combinations versus standard of care in cancer: a systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Oncoimmunology"
DOI: 10.1080/2162402x.2021.1878599
Abstract: ABSTRACT Immune checkpoint inhibitors (ICIs) as monotherapy in different solid tumors showed an early detrimental effect in a subset of patients reflected by the early crossover of the progression-free survival (PFS) curves. Currently, combination therapies… read more here.
Keywords: efficacy safety; combinations versus; standard care; anti combinations ... See more keywords
The efficacy and safety of anti-PD-1/PD-L1 antibodies for treatment of advanced or refractory cancers: A meta-analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e23075
Abstract: e23075Background: Immunotherapy based on anti-PD-1 (Programmed death 1)/PD-L1 (PD-1 Ligand 1) antibodies have achieved significant successes from bench to clinic. In this study, we systematically e... read more here.
Keywords: advanced refractory; efficacy safety; treatment advanced; safety anti ... See more keywords
Safety, PK/PD, and anti-tumor activity of RO6874281, an engineered variant of interleukin-2 (IL-2v) targeted to tumor-associated fibroblasts via binding to fibroblast activation protein (FAP).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e15155
Abstract: e15155Background: High-dose (HD) IL-2 is approved for patients with melanoma and renal cell carcinoma but is associated with significant toxicity, given only in an inpatient setting. RO6874281 is a... read more here.
Keywords: tumor activity; safety anti; anti tumor; ro6874281 engineered ... See more keywords
Efficacy and Safety of Anti-Tumor Necrosis Factor-Alpha Agents for Patients with Intestinal Behcet’s Disease: A Systematic Review and Meta-Analysis
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DOI: 10.3349/ymj.2022.63.2.148
Abstract: Purpose Intestinal Behcet’s disease (BD) is a systemic autoimmune disease for which treatment options are limited. As a prospective therapeutic strategy for intestinal BD, anti-tumor necrosis factor-alpha (anti-TNF-α) agents have received increasing attention. In this… read more here.
Keywords: anti tnf; safety; tnf agents; safety anti ... See more keywords
COVID-19 Pandemic: What about the Safety of Anti-Coronavirus Nanoparticles?
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DOI: 10.3390/nano11030796
Abstract: Every day, new information is presented with respect to how to best combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This manuscript sheds light on such recent findings, including new co-factors (i.e., neuropilin-1) and… read more here.
Keywords: anti coronavirus; safety anti; coronavirus; pandemic safety ... See more keywords
Immunogenicity and Safety of Anti-SARS-CoV-2 mRNA Vaccines in a Cohort of Patients with Hereditary Angioedema
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DOI: 10.3390/vaccines11020215
Abstract: Many factors may trigger hereditary angioedema (HAE) attacks. This study aims to gain insights into the benefits and potential risks of COVID-19 vaccination in HAE patients, focusing particularly on the possibility of triggering attacks. We… read more here.
Keywords: immunogenicity safety; hereditary angioedema; cov mrna; safety anti ... See more keywords