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Published in 2017 at "American Journal of Cardiovascular Drugs"
DOI: 10.1007/s40256-017-0214-7
Abstract: BackgroundDespite extensive use of statins, patients with hypercholesterolemia, especially homozygous familial hypercholesterolemia (HoFH), do not achieve recommended targets of low-density lipoprotein cholesterol (LDL-C). There is an urgent need for novel options that could reduce proatherogenic…
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Keywords:
hofh;
hypercholesterolemia;
efficacy safety;
cholesterol ... See more keywords
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Published in 2021 at "European journal of preventive cardiology"
DOI: 10.1093/eurjpc/zwab229
Abstract: BACKGROUND Lomitapide is a lipid-lowering agent indicated as adjunct therapy for adult HoFH. OBJECTIVES This study evaluated the medium-term effectiveness and safety of lomitapide in a large cohort of HoFH patients in Europe. METHODS In…
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Keywords:
safety;
retrospective observational;
hofh patients;
safety lomitapide ... See more keywords