Efficacy and safety of pemafibrate (K-877), a selective peroxisome proliferator-activated receptor α modulator, in patients with dyslipidemia: Results from a 24-week, randomized, double blind, active-controlled, phase 3 trial.
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DOI: 10.1016/j.jacl.2017.10.006
Abstract: BACKGROUND To overcome the concerns associated with the use of fibrates, pemafibrate (K-877), a novel selective peroxisome proliferator-activated receptor modulator, was developed. In a previous phase 2 trial, we showed excellent efficacy and safety of… read more here.
Keywords: efficacy safety; safety; safety pemafibrate; fenofibrate ... See more keywords
Efficacy and Safety of Pemafibrate Versus Bezafibrate to Treat Patients with Hypertriglyceridemia: A Randomized Crossover Study
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DOI: 10.5551/jat.63659
Abstract: Aim: Pemafibrate is a highly selective agonist for peroxisome proliferator-activated receptor (PPAR)-α, a key regulator of lipid and glucose metabolism. We compared the efficacy and safety of pemafibrate with those of bezafibrate, a nonselective PPAR-α… read more here.
Keywords: pemafibrate; safety pemafibrate; randomized crossover; pemafibrate bezafibrate ... See more keywords