An update on phosphate binders for the treatment of hyperphosphatemia in chronic kidney disease patients on dialysis: a review of safety profiles
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2022.2044472
Abstract: ABSTRACT Introduction Hyperphosphatemia is an inevitable complication for patients undergoing dialysis, as is the resulting need for treatment with phosphate binders. Currently, various phosphate binders are clinically available. In addition to their phosphate-lowering activity, individual… read more here.
Keywords: phosphate; hyperphosphatemia; safety profiles; treatment ... See more keywords
Review of the Safety Profiles of Laxatives in Pregnant Women
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000001660
Abstract: Chronic constipation is one of the most common complaints seen in the gastroenterology clinic and is particularly prevalent in women. Women who become pregnant may suffer from existing constipation or develop constipation de novo. A… read more here.
Keywords: constipation; gastroenterology; profiles laxatives; safety ... See more keywords
Efficacy and safety profiles of mood stabilizers and antipsychotics for bipolar depression: a systematic review
Sign Up to like & getrecommendations! Published in 2023 at "International Clinical Psychopharmacology"
DOI: 10.1097/yic.0000000000000449
Abstract: The whole picture of psychotropics for bipolar depression (BPD) remains unclear. This review compares the differences in efficacy and safety profiles among common psychotropics for BPD. MEDLINE, EMBASE, and PsycINFO were searched for proper studies.… read more here.
Keywords: efficacy safety; efficacy; bipolar depression; safety profiles ... See more keywords
Abstract LB031: SHR-A1811, a novel anti-HER2 ADC with superior bystander effect, optimal DAR and favorable safety profiles
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb031
Abstract: Current clinical HER2-targeting ADCs, especially T-DXd, have shown strong efficacy in HER2-expressing/mutant cancers, however, with adverse events such as hematologic toxicities and interstitial lung disease (ILD)/pneumonitis. Here we presented a potential best-in-class HER2-directed ADC, SHR-A1811,… read more here.
Keywords: safety profiles; shr a1811; cancer; her2 ... See more keywords
Comparative quantitative safety profiles of PD-1 and PD-L1 checkpoint inhibitor monotherapies: A Bayesian model-based meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e15167
Abstract: e15167Background: Anti-cancer therapies with immune checkpoint inhibitors (ICIs) are associated with immune-mediated adverse events (imAEs). The objective of this study was to use a Bayesian model-... read more here.
Keywords: safety profiles; bayesian model; model; quantitative safety ... See more keywords
Predictive Value of Albumin and Neutrophil-to-Lymphocyte Ratio Score for Treatment Completeness and Safety Profiles in Patients With Head and Neck Cancer Receiving Definitive Concurrent Chemoradiotherapy
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DOI: 10.21873/invivo.13028
Abstract: Abstract Background/Aim: Malnutrition and inflammation are common conditions in patients with head and neck cancer (HNC). This study aimed to evaluate the predictive value of albumin combined with neutrophil-lymphocyte ratio (NLR), referring to the albumin-NLR… read more here.
Keywords: completeness; treatment completeness; value; safety profiles ... See more keywords
Molecular Insights of SARS-CoV-2 Antivirals Administration: A Balance between Safety Profiles and Impact on Cardiovascular Phenotypes
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10020437
Abstract: The COVID-19 pandemic has resulted in a complex clinical challenge, caused by a novel coronavirus, partially similar to previously known coronaviruses but with a different pattern of contagiousness, complications, and mortality. Since its global spread,… read more here.
Keywords: safety profiles; impact cardiovascular; molecular insights; administration ... See more keywords
Effectiveness and Safety Profiles of Biological Therapies in Inflammatory Bowel Disease: Real Life Data from an Active Pharmacovigilance Project
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DOI: 10.3390/biomedicines10123280
Abstract: Post-marketing surveillance is essential to evaluate the risk/benefit profile of drugs; however, pharmacovigilance studies comparing persistence and safety of biologic therapies in patients with inflammatory bowel disease (IBD) are scant. The aim of this study… read more here.
Keywords: persistence; safety; inflammatory bowel; bowel disease ... See more keywords
Safety profiles of new xanthine oxidase inhibitors: A post-marketing study.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of clinical pharmacology and therapeutics"
DOI: 10.5414/cp203898
Abstract: INTRODUCTION The development of new xanthine oxidase (XO) inhibitors, such as febuxostat and topiroxostat, could offer an alternative to treatment with allopurinol. The purpose of this study was to compare safety profiles of new XO… read more here.
Keywords: profiles new; xanthine oxidase; new xanthine; oxidase inhibitors ... See more keywords