Hyperoxidized albumin modulates neutrophils to induce oxidative stress and inflammation in severe alcoholic hepatitis
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28897
Abstract: Albumin is a potent scavenger of reactive oxygen species (ROS). However, modifications in albumin structure may reduce its antioxidant properties and modulate its immune‐regulatory functions. We examined alterations in circulating albumin in severe alcoholic hepatitis… read more here.
Keywords: severe alcoholic; stress; albumin; sah ... See more keywords
Eupatilin alleviates inflammatory response after subarachnoid hemorrhage by inhibition of TLR4/MyD88/NF‐κB axis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23317
Abstract: Early brain injury (EBI) is associated with the adverse prognosis of subarachnoid hemorrhage (SAH) patients. The key bioactive component of the Chinese herbal medicine Artemisia asiatica Nakai (Asteraceae) is eupatilin. Recent research reports that eupatilin… read more here.
Keywords: subarachnoid hemorrhage; brain; eupatilin; tlr4 myd88 ... See more keywords
Gastrointestinal digestion and absorption characterization in vitro of zinc-chelating hydrolysate from scallop adductor (Patinopecten yessoensis).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11673
Abstract: BACKGROUD Zinc is an essential catalytic element in human health system but its absorption in intestinal system could be strongly affected by the gastrointestinal digestion. In this study, the food-derived potential zinc carrier, scallop adductor… read more here.
Keywords: zinc; digestion; zinc chelating; scallop adductor ... See more keywords
Are modified Fisher Scale and bleeding pattern helpful predictors of neurological complications in non-aneurysmal subarachnoid hemorrhage?
Sign Up to like & getrecommendations! Published in 2020 at "Neuroradiology"
DOI: 10.1007/s00234-020-02524-7
Abstract: Non-aneurysmal subarachnoid hemorrhage (NA-SAH) is a clinical-radiological entity with a different prognosis than aneurysmal SAH (A-SAH). The purpose of this study is to assess the predictive value of the modified Fisher Scale (mFS) for neurological… read more here.
Keywords: aneurysmal subarachnoid; modified fisher; subarachnoid hemorrhage; non aneurysmal ... See more keywords
Predictive factors and timelines of rebleeding in aneurysmal SAH: what have we gleaned?
Sign Up to like & getrecommendations! Published in 2021 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-021-04772-9
Abstract: Dear Editor, We read with great interest the recently published article by Sorteberg et al. [4] on the timelines of aneurysmal subarachnoid haemorrhage (aSAH) rebleeds. We would like to complement the authors for their attempt… read more here.
Keywords: predictive factors; rebleed; treatment; aneurysmal sah ... See more keywords
Paeoniflorin attenuates early brain injury through reducing oxidative stress and neuronal apoptosis after subarachnoid hemorrhage in rats
Sign Up to like & getrecommendations! Published in 2020 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-020-00571-w
Abstract: Paeoniflorin is a natural monoterpene glucoside from Paeoniae Radix with neuroprotective properties. However, it is still unclear whether paeoniflorin has neuroprotective effects on subarachnoid hemorrhage (SAH). This study explores the effect of paeoniflorin on early… read more here.
Keywords: early brain; subarachnoid hemorrhage; brain injury; brain ... See more keywords
Practice Variation in the Diagnosis of Aneurysmal Subarachnoid Hemorrhage: A Survey of US and Canadian Emergency Medicine Physicians
Sign Up to like & getrecommendations! Published in 2019 at "Neurocritical Care"
DOI: 10.1007/s12028-019-00679-7
Abstract: Background and AimsSpontaneous subarachnoid hemorrhage (SAH) from a brain aneurysm, if untreated in the acute phase, leads to loss of functional independence in about 30% of patients and death in 27–44%. To evaluate for SAH,… read more here.
Keywords: medicine; variation; survey; emergency ... See more keywords
Intranasal Insulin Treatment Attenuates Metabolic Distress and Early Brain Injury After Subarachnoid Hemorrhage in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Neurocritical Care"
DOI: 10.1007/s12028-020-01011-4
Abstract: Background Intranasal administration of insulin to the brain bypasses the blood brain barrier (BBB) and can increase cerebral glucose uptake and prevent energy failure. Intranasal insulin treatment has shown neuroprotective effects in multiple central nervous… read more here.
Keywords: brain; insulin treatment; intranasal insulin; sah ... See more keywords
Inflammasome Caspase-1 Activity is Elevated in Cerebrospinal Fluid After Aneurysmal Subarachnoid Hemorrhage and Predicts Functional Outcome
Sign Up to like & getrecommendations! Published in 2020 at "Neurocritical Care"
DOI: 10.1007/s12028-020-01113-z
Abstract: Subarachnoid hemorrhage (SAH) is a devastating neurological injury, further complicated by few available methods to objectively predict outcomes. With the recent shift in focus to neuroinflammation as a potential cause of adverse outcomes following SAH,… read more here.
Keywords: caspase activity; caspase; functional outcome; sah ... See more keywords
Fucoxanthin Mitigates Subarachnoid Hemorrhage-Induced Oxidative Damage via Sirtuin 1-Dependent Pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular neurobiology"
DOI: 10.1007/s12035-020-02095-x
Abstract: Oxidative stress is a key component of the pathological cascade in subarachnoid hemorrhage (SAH). Fucoxanthin (Fx) possesses a strong antioxidant property and has shown neuroprotective effects in acute brain injuries such as ischemic stroke and… read more here.
Keywords: oxidative damage; induced oxidative; subarachnoid hemorrhage; via sirtuin ... See more keywords
The Stabilization of Central Sympathetic Nerve Activation by Renal Denervation Prevents Cerebral Vasospasm after Subarachnoid Hemorrhage in Rats
Sign Up to like & getrecommendations! Published in 2019 at "Translational Stroke Research"
DOI: 10.1007/s12975-019-00740-9
Abstract: The poor prognosis of subarachnoid hemorrhage (SAH) might be associated with sympathetic nerve activation (catecholamine surge) initiated by hypothalamic injury. As renal denervation (RD) has been shown to exert protective effects on cardiovascular dysfunction by… read more here.
Keywords: sah; nerve activation; central sympathetic; sympathetic nerve ... See more keywords