Saikosaponin A attenuates perimenopausal depression-like symptoms by chronic unpredictable mild stress
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.09.046
Abstract: Accumulating studies have shown that a traditional Chinese decoction Chaihu-Shugan-San produced the antidepressant-like effects in rodents including in perimenopausal. Previous studies and our preliminary study indicated that saikosaponin A, one of the main constituents of… read more here.
Keywords: chronic unpredictable; saikosaponin; test; unpredictable mild ... See more keywords
Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma
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DOI: 10.1155/2022/5489553
Abstract: Saikosaponin D (SSD), a saponin derivative, is extracted from Bupleurum falcatum. It exhibits an inhibitory effect on a number of tumor cells and is relatively safe when used at therapeutic doses. However, its effects on… read more here.
Keywords: endoplasmic reticulum; saikosaponin; reticulum stress; apoptosis autophagy ... See more keywords
Saikosaponin-d Attenuates Hashimoto's Thyroiditis by Regulating Macrophage Polarization
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/7455494
Abstract: Objective Hashimoto's thyroiditis (HT) is one of the most common clinical autoimmune diseases. Recent studies have found that HT pathogenesis is associated with macrophage polarization. Saikosaponin-d (SSd) is an active component in the Chinese medicine… read more here.
Keywords: hashimoto thyroiditis; macrophage polarization; saikosaponin; polarization ... See more keywords
Bupleurum scorzonerifolium: Systematic research through pharmacodynamics and serum pharmacochemistry on screening antidepressant Q-markers for quality control.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.2139/ssrn.4231973
Abstract: Bupleurum scorzonerifolium (BS) is one of the sources of Bupleuri Radix, which was first recorded in Shennong's classic of materia medica. It has a medicinal history of 2000 years and is now widely used for… read more here.
Keywords: saikosaponin; bupleurum scorzonerifolium; depression; quality ... See more keywords
Production of Prosaikogenin F, Prosaikogenin G, Saikogenin F and Saikogenin G by the Recombinant Enzymatic Hydrolysis of Saikosaponin and their Anti-Cancer Effect
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27103255
Abstract: The saponins of Bupleurum falcatum L., saikosaponins, are the major components responsible for its pharmacological and biological activities. However, the anti-cancer effects of prosaikogenin and saikogenin, which are glycoside hydrolyzed saikosaponins, are still unknown due… read more here.
Keywords: prosaikogenin saikogenin; saikosaponin; anti cancer; prosaikogenin ... See more keywords
Saikosaponin A and Its Epimers Alleviate LPS-Induced Acute Lung Injury in Mice
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28030967
Abstract: The purpose of this work was to illustrate the effect of processing with vinegar on saikosaponins of Bupleurum chinense DC. (BC) and the protective effects of saikosaponin A (SSA), saikosaponin b1 (SSb1), saikosaponin b2 (SSb2),… read more here.
Keywords: acute lung; saikosaponin; lung injury; induced acute ... See more keywords