Comparison of expression optimization of new derivative of staphylokinase (SAK‐2RGD‐TTI) with the rSAK
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DOI: 10.1002/btpr.2819
Abstract: Staphylokinase (SAK) is a promising thrombolytic agent for the treatment of patients suffering from blood‐clotting disorders. To increase the potency of SAK and to minimize vessel reocclusion, a new construct bearing SAK motif fused to… read more here.
Keywords: 2rgd tti; sak 2rgd; staphylokinase sak; expression ... See more keywords
Designing a multifunctional staphylokinase variant (SAK-2RGD-TTI) with appropriate thrombolytic activity in vitro
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Letters"
DOI: 10.1007/s10529-019-02748-5
Abstract: Objective Thrombin, platelets, and plasmin are three key factors involved in hemostasis and thrombolysis. Thrombolytic therapy with clinically approved drugs is often followed by recurrent thrombosis caused by thrombin-induced platelet aggregation from the clot debris.… read more here.
Keywords: clot; 2rgd tti; staphylokinase; designing multifunctional ... See more keywords