Coordination chemistry of Zn2+ with Sal(ph)en ligands: Tetrahedral coordination or penta‐coordination? a DFT analysis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.25755
Abstract: In this article, the Lewis acidic character within a series of Zn‐Sal(ph)en complexes is reviewed and revisited. Besides traditional analyses found in the literature, conceptual density functional theory descriptors are used to assess this acidic… read more here.
Keywords: dual descriptor; coordination; sal; chemistry ... See more keywords
Ancient herbal component may be a novel therapeutic for gouty arthritis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ce1018-384r
Abstract: Rhodiola species are flowering perennial plants in Crassulaceae family that have been used in folk medicine in Asia and Europe for thousands of years. In traditional Chinese medicine, Rhodiola species was initially documented in Sheng… read more here.
Keywords: gouty; medicine; sal; rhodiola species ... See more keywords
Polymeric Micellar Formulation Enhances Antimicrobial and Anticancer Properties of Salinomycin
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Research"
DOI: 10.1007/s11095-019-2615-6
Abstract: PurposeSalinomycin (SAL) is a polyether compound that exhibits strong antimicrobial as well as anticancer activity. Nanomedicine has been at the forefront of drug delivery research with the aim of increasing the efficacy, specificity and reduce… read more here.
Keywords: antimicrobial anticancer; sal; cancer; cell ... See more keywords
Enhancing mechanical properties of epoxy resin using waste lignin and salicylate alumoxane nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "Korean Journal of Chemical Engineering"
DOI: 10.1007/s11814-017-0301-0
Abstract: Extracted lignin from wastewater of Kraft process and lab-made salicylate alumoxane (Sal-A) nanoparticles were used as toughening agents in epoxy matrix. Epoxy/lignin composite, epoxy/Sal-A and epoxy/lignin/Sal-Al nanocomposites with various toughening agent loadings were cured with… read more here.
Keywords: microscopy; sal; sal nanoparticles; lignin sal ... See more keywords
Salidroside alleviates high glucose-induced oxidative stress and extracellular matrix accumulation in rat glomerular mesangial cells by the TXNIP-NLRP3 inflammasome pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2017.10.012
Abstract: Diabetic nephropathy (DN) is a metabolic disease characterized by mesangial cell proliferation and extracellular matrix (ECM) accumulation. Salidroside (SAL) is the major ingredient in Rhodiola rosea and possesses beneficial effects on DN. This study aimed… read more here.
Keywords: accumulation; sal; txnip nlrp3; nlrp3 inflammasome ... See more keywords
Anti-trypanosomal activity of doubly modified salinomycin derivatives.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.03.061
Abstract: As a group of biologically active compounds, polyether antibiotics (ionophores) show a broad spectrum of interesting pharmacological properties, ranging from anti-bacterial to anti-cancer activities. There is increasing evidence that ionophores, including salinomycin (SAL), and their… read more here.
Keywords: trypanosomal activity; sal; doubly modified; anti trypanosomal ... See more keywords
Ester derivatives of salinomycin efficiently eliminate breast cancer cells via ER-stress-induced apoptosis.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173824
Abstract: The polyether ionophore salinomycin (SAL) has been found to selectively target breast cancer cells, including those with stem-like phenotype. On the other hand, SAL amides and esters obtained through derivatisation of the C1 carboxyl of… read more here.
Keywords: sal; ester derivatives; breast cancer; cancer cells ... See more keywords
Does total shoulder arthroplasty improve patients' activity levels?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of shoulder and elbow surgery"
DOI: 10.1016/j.jse.2018.03.028
Abstract: BACKGROUND Total shoulder arthroplasty (TSA) decreases pain, improves range of motion, and increases strength. Whether these improvements translate to improvements in activity levels postoperatively remains unknown. The Shoulder Activity Level (SAL) is a valid and… read more here.
Keywords: shoulder arthroplasty; sal; tsa; shoulder ... See more keywords
Salvianolic acid B exerts anti-liver fibrosis effects via inhibition of MAPK-mediated phospho-Smad2/3 at linker regions in vivo and in vitro.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.116881
Abstract: AIM To investigate anti-liver fibrosis effects of Salvianolic acid B (Sal B) from Salvia miltiorrhiza Bunge involved mitogen-activated protein kinase (MAPK)-mediated transforming growth factor-beta (TGF-β) signaling. MAIN METHODS Diethylnitrosamine (DEN)-induced liver fibrosis in mice and… read more here.
Keywords: fibrosis; liver fibrosis; sal; tgf ... See more keywords
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3
Sign Up to like & getrecommendations! Published in 2018 at "Mechanisms of Ageing and Development"
DOI: 10.1016/j.mad.2017.12.005
Abstract: OBJECTIVE Endothelial cellular senescence is an important contributor to the endothelial dysfunction and atherosclerosis. Our previous studies suggested that salidroside (SAL) can alleviate atherosclerosis and protect endothelial cells against oxidative stress induced damage. However, the… read more here.
Keywords: expression inflammatory; sal; endothelial cellular; senescence ... See more keywords
Participation of acetylcholine and its receptors in the contractility of inflamed porcine uterus.
Sign Up to like & getrecommendations! Published in 2019 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2019.09.015
Abstract: This study analyzed the effect of inflammation on acetylcholine (ACh)-induced muscarinic receptors (MR)2 and MR3 conducted contractility of the porcine uterus. On Day 3 of the estrous cycle, either E.coli suspension (E.coli group) or saline… read more here.
Keywords: endo myo; coli group; sal; group ... See more keywords