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   Articles with "salidroside" as a keyword



Salidroside alleviates ulcerative colitis via inhibiting macrophage pyroptosis and repairing the dysbacteriosis‐associated Th17/Treg imbalance

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recommendations! Published in 2022 at "Phytotherapy Research"

DOI: 10.1002/ptr.7636

Abstract: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by flora disequilibrium and mucosal immunity disorder. Here, we report that salidroside effectively restricts experimental colitis from two aspects of intestinal macrophage pyroptosis and dysbacteriosis‐derived… read more here.

Keywords: macrophage pyroptosis; th17 treg; pyroptosis; colitis ... See more keywords

Salidroside ameliorates pathological cardiac hypertrophy via TLR4‐TAK1‐dependent signaling

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recommendations! Published in 2022 at "Phytotherapy Research"

DOI: 10.1002/ptr.7701

Abstract: Salidroside, a prominent active ingredient in traditional Chinese medicines, is garnering increased attention because of its unique pharmacological effects against ischemic heart disease via MAPK signaling, which plays a critical role in regulating the evolution… read more here.

Keywords: hypertrophy; jnk p38; tak1; tlr4 ... See more keywords

Salidroside Restores an Anti-inflammatory Endothelial Phenotype by Selectively Inhibiting Endothelial Complement After Oxidative Stress

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recommendations! Published in 2019 at "Inflammation"

DOI: 10.1007/s10753-019-01121-y

Abstract: Salidroside, an active component of Rhodiola rosea , reduces inflammation and neuronal damage after middle cerebral artery occlusion (MCAO) with reperfusion, partly by inhibiting cerebral complement C3 activation. However, the mechanisms of this inhibition are… read more here.

Keywords: anti inflammatory; inflammatory endothelial; oxidative stress; complement ... See more keywords

Salidroside suppresses the activation of nasopharyngeal carcinoma cells via targeting miR-4262/GRP78 axis

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recommendations! Published in 2022 at "Cell Cycle"

DOI: 10.1080/15384101.2021.2019976

Abstract: ABSTRACT To study the effect of Salidroside on nasopharyngeal carcinoma (NPC) cells and its mechanism. NPC cells were cultured, MTT was used to detect the effect of Salidroside on cell proliferation, apoptosis detected by flow… read more here.

Keywords: nasopharyngeal carcinoma; expression; mir 4262; 4262 grp78 ... See more keywords

Salidroside protect Chinese hamster V79 cells from genotoxicity and oxidative stress induced by CL-20.

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recommendations! Published in 2023 at "Toxicology research"

DOI: 10.1093/toxres/tfad004

Abstract: Hexanitrohexaazaisowurtzitane (CL-20) is a high-energy elemental explosive widely used in chemical and military fields. CL-20 harms environmental fate, biosafety, and occupational health. However, there is little known about the genotoxicity of CL-20, in particular its… read more here.

Keywords: genotoxicity; salidroside; oxidative stress; v79 cells ... See more keywords

Salidroside protects RGC from pyroptosis in diabetes-induced retinopathy associated with NLRP3, NFEZL2 and NGKB1, revealed by network pharmacology analysis and experimental validation

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recommendations! Published in 2024 at "European Journal of Medical Research"

DOI: 10.1186/s40001-023-01578-6

Abstract: To investigate the effect of salidroside (SAL) in protecting retinal ganglion cell (RGC) from pyroptosis and explore associated molecular network mechanism in diabetic retinapathy (DR) rats. HE, Nissl and immunofluorescence staining were used to observe… read more here.

Keywords: pyroptosis; salidroside; rgc pyroptosis; analysis ... See more keywords

Salidroside enhances NO bioavailability and modulates arginine metabolism to alleviate pulmonary arterial hypertension

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recommendations! Published in 2024 at "European Journal of Medical Research"

DOI: 10.1186/s40001-024-02016-x

Abstract: Salidroside (SAL), derived from Rhodiola, shows protective effects in pulmonary arterial hypertension (PAH) models, but its mechanisms are not fully elucidated. Investigate the therapeutic effects and the mechanism of SAL on PAH. Monocrotaline was used… read more here.

Keywords: sal; arterial hypertension; salidroside; arginine metabolism ... See more keywords

Controlled Release of Salidroside Microspheres Prepared Using a Chitosan and Methylcellulose Interpenetrating Polymer Network

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recommendations! Published in 2017 at "International Journal of Food Engineering"

DOI: 10.1515/ijfe-2017-0236

Abstract: Abstract In this work, salidroside, a functional food agent, was incorporated into novel interpenetrating polymer network microspheres (IPN-Ms) prepared by chitosan (CS) and methylcellulose (MC) for controlled release and stabilization. IPN-Ms were characterized using scanning… read more here.

Keywords: network; controlled release; salidroside; chitosan methylcellulose ... See more keywords

Salidroside - Can it be a multifunctional drug?

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recommendations! Published in 2020 at "Current drug metabolism"

DOI: 10.2174/1389200221666200610172105

Abstract: BACKGROUND Salidroside is a glucoside of tyrosol found mostly in the roots of Rhodiola spp. It exhibits diverse biological and pharmacological properties. In the last decade, enormous research is conducted to explore the medicinal properties… read more here.

Keywords: salidroside multifunctional; metabolism; multifunctional drug; anti ... See more keywords

Long-Term Oral Administration of Salidroside Alleviates Diabetic Retinopathy in db/db Mice

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recommendations! Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.861452

Abstract: Diabetic retinopathy (DR), a microvascular complication of diabetes mellitus, is the leading cause of vision loss in the working-age population worldwide. Unfortunately, current clinical treatments cannot completely prevent the occurrence and development of DR. Salidroside… read more here.

Keywords: sal treatment; diabetic mice; mice; diabetic retinopathy ... See more keywords

Salidroside inhibits migration, invasion and angiogenesis of MDA‑MB 231 TNBC cells by regulating EGFR/Jak2/STAT3 signaling via MMP2.

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recommendations! Published in 2018 at "International journal of oncology"

DOI: 10.3892/ijo.2018.4430

Abstract: The major hallmarks of tumor progression are angiogenesis, migration and metastasis. Among the components of Rhodiola rosea, salidroside (p‑hydroxyphenethyl-β‑d-glucoside) is one of the most potent, and is present in all Rhodiola species. Recent data have… read more here.

Keywords: angiogenesis; invasion; salidroside; migration ... See more keywords