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   Articles with "salivarius" as a keyword



Airway Delivery of Streptococcus Salivarius is Sufficient to Induce Experimental Pulmonary Hypertension in Rat.

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recommendations! Published in 2023 at "British journal of pharmacology"

DOI: 10.1111/bph.16064

Abstract: BACKGROUND AND PURPOSE The causal relationship between altered host microbiome composition, especially the respiratory tract microbiome, and the occurrence of pulmonary hypertension (PH) has not yet been studied. An increased abundance of airway streptococci is… read more here.

Keywords: pulmonary hypertension; salivarius induced; salivarius; streptococcus salivarius ... See more keywords

Streptococcus salivarius-derived ilexgenin A alleviates pneumonia through the gut-lung axis

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recommendations! Published in 2025 at "mSystems"

DOI: 10.1128/msystems.00731-25

Abstract: ABSTRACT The alteration of gut microbiota during critical illness is associated with adverse clinical outcomes. This connection between intestinal dysbiosis and poor outcomes has prompted the idea that restoring healthy microbial communities could offer a… read more here.

Keywords: gut microbiota; salivarius; streptococcus salivarius; pneumonia ... See more keywords

Abstract 1181: Therapeutic efficacy by Streptococcus salivarius as a probiotic in a preclinical model of oropharyngeal carcinoma

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recommendations! Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-1181

Abstract: Streptococcus salivarius is a gram-positive, non-pathogenic bacteria found in the oral cavity and upper respiratory tract. This bacterium has been shown to possess antimicrobial properties with the potential to cause activation of natural killer (NK)… read more here.

Keywords: cancer; therapeutic efficacy; streptococcus salivarius; salivarius probiotic ... See more keywords

Safety Assessment of Streptococcus salivarius UBSS-01 in Rats and Double-Blind Placebo-Controlled Study in Healthy Individuals

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recommendations! Published in 2024 at "International Journal of Toxicology"

DOI: 10.1177/10915818241247527

Abstract: Streptococcus salivarius is a common, harmless, and prevalent member of the oral microbiota in humans. In the present study, the safety of S. salivarius UBSS-01 was evaluated using in silico methods and preclinical and clinical… read more here.

Keywords: double blind; streptococcus salivarius; salivarius ubss; salivarius ... See more keywords

Competence shut-off by intracellular pheromone degradation in salivarius streptococci

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recommendations! Published in 2022 at "PLoS Genetics"

DOI: 10.1371/journal.pgen.1010198

Abstract: Competence for DNA transformation is a major strategy for bacterial adaptation and survival. Yet, this successful tactic is energy-consuming, shifts dramatically the metabolism, and transitory impairs the regular cell-cycle. In streptococci, complex regulatory pathways control… read more here.

Keywords: competence; pheromone degradation; salivarius; streptococci ... See more keywords

Use of Streptococcus salivarius K12 in supporting the mucosal immune function of active young subjects: A randomised double-blind study

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recommendations! Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1129060

Abstract: Introduction Upper respiratory tract infections (URTI) are the most common illnesses affecting athletes, causing absences from training and competition. Salivary immunoglobulin A (sIgA) is the main immune factor in saliva, and a consistent association between… read more here.

Keywords: young subjects; salivarius; salivarius k12; active young ... See more keywords

Gut Microbiota and Immune Modulatory Properties of Human Breast Milk Streptococcus salivarius and S. parasanguinis Strains

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recommendations! Published in 2022 at "Frontiers in Nutrition"

DOI: 10.3389/fnut.2022.798403

Abstract: Human breast milk Streptococcus spp. are transferred to infant guts via breast feeding, but their effects on the gut microbiota and immunity remain unclear. In this study, we characterized gut microbiota and immune modulatory properties… read more here.

Keywords: gut microbiota; breast; salivarius; milk ... See more keywords
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Abundance, Diversity and Role of ICEs and IMEs in the Adaptation of Streptococcus salivarius to the Environment

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recommendations! Published in 2020 at "Genes"

DOI: 10.3390/genes11090999

Abstract: Streptococcus salivarius is a significant contributor to the human oral, pharyngeal and gut microbiomes that contribute to the maintenance of health. The high genomic diversity observed in this species is mainly caused by horizontal gene… read more here.

Keywords: diversity; salivarius; role; streptococcus salivarius ... See more keywords

Colonizing Bacteria Aggravate Inflammation, Cytotoxicity and Immune Defense During Influenza A Virus Infection

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recommendations! Published in 2025 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms26115364

Abstract: A diverse bacterial community colonizes the respiratory system, including commensals such as Staphylococcus epidermidis (S. epidermidis) and Streptococcus salivarius (S. salivarius), as well as facultative pathogens like Staphylococcus aureus (S. aureus). This study aimed to… read more here.

Keywords: aureus; cytotoxicity; inflammation; infection ... See more keywords

Multi-Strain Probiotic Supplementation with a Product Containing Human-Native S. salivarius K12 in Healthy Adults Increases Oral S. salivarius

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recommendations! Published in 2021 at "Nutrients"

DOI: 10.3390/nu13124392

Abstract: Streptococcus salivarius (S. salivarius) K12 supplementation has been found to reduce the risk of recurrent upper respiratory tract infections. Yet, studies have not reported the effect of supplementation on oral S. salivarius K12 levels or… read more here.

Keywords: oral salivarius; supplementation; healthy adults; salivarius ... See more keywords

Safety assessment of Streptococcus salivarius M18 a probiotic for oral health.

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recommendations! Published in 2022 at "Beneficial microbes"

DOI: 10.3920/bm2021.0107

Abstract: The development of probiotics targeting non-intestinal body sites continues to generate interest amongst researchers, biotech companies and consumers alike. A key consideration for any bacterial strain to be developed into a probiotic is a robust… read more here.

Keywords: safety; oral health; salivarius; strain m18 ... See more keywords