Paired related homeobox 1 attenuates autophagy via acetyl‐CoA carboxylase 1‐regulated fatty acid metabolism in salivary adenoid cystic carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13367
Abstract: Autophagy can affect the invasion and metastasis of carcinoma. Our previous study has shown that invasion and epithelial‐mesenchymal transition in salivary adenoid cystic carcinoma (SACC) can be promoted by the metabolic reprogramming of free fatty… read more here.
Keywords: adenoid cystic; autophagy via; salivary adenoid; cystic carcinoma ... See more keywords
Exosomal microRNA-23b-3p promotes tumor angiogenesis and metastasis by targeting PTEN in Salivary adenoid cystic carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Carcinogenesis"
DOI: 10.1093/carcin/bgac033
Abstract: MicroRNA(miR)-23b-3p is known to target various genes that are involved in cancer-related pathways. Exosomes are emerging intercellular communication agents. Exosomes secreted by cancer cells can deliver active molecules to the surrounding stromal cells, thereby influencing… read more here.
Keywords: sacc; salivary adenoid; angiogenesis; exosomal mir ... See more keywords
miR-582-5p inhibits invasion and migration of salivary adenoid cystic carcinoma cells by targeting FOXC1
Sign Up to like & getrecommendations! Published in 2017 at "Japanese Journal of Clinical Oncology"
DOI: 10.1093/jjco/hyx073
Abstract: Objective Neurotropism of salivary adenoid cystic carcinoma (SACC) and pulmonary metastasis may lead to in treatment failure. miR-582-5p plays important roles in tumorigenesis, invasion and migration. Here, we aim to determine the effect of miR-582-5p… read more here.
Keywords: sacc; invasion migration; mir 582; salivary adenoid ... See more keywords
Cytokeratin-14 contributes to collective invasion of salivary adenoid cystic carcinoma
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DOI: 10.1371/journal.pone.0171341
Abstract: Collective invasion of cells plays a fundamental role in tissue growth, wound healing, immune response and cancer metastasis. This paper aimed to investigate cytokeratin-14 (CK14) expression and analyze its association with collective invasion in the… read more here.
Keywords: sacc; ck14; invasion; salivary adenoid ... See more keywords
Tumor-derived exosomes educate fibroblasts to promote salivary adenoid cystic carcinoma metastasis via NGF-NTRK1 pathway
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DOI: 10.3892/ol.2019.10740
Abstract: Salivary adenoid cystic carcinoma (SACC) is a rare head and neck malignancy characterized by unpredictable expansion, considerable perineural invasion and high risk of metastasis; however, the underlying mechanism of SACC progression remains unclear. Cancer-associated fibroblasts… read more here.
Keywords: sacc; salivary adenoid; metastasis; cystic carcinoma ... See more keywords
The NOTCH1-HEY1 pathway regulates self-renewal and epithelial-mesenchymal transition of salivary adenoid cystic carcinoma cells
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.36407
Abstract: Our previous study demonstrated a close relationship between the NOTCH signaling pathway and salivary adenoid cystic carcinoma (SACC). Its receptor gene, NOTCH1, and its downstream gene, HES1, contribute to the proliferation, invasion and metastasis of… read more here.
Keywords: sacc; notch1 hey1; hey1 pathway; salivary adenoid ... See more keywords