Regulators of Salmonella-host interaction identified by peripheral blood transcriptome profiling: roles of TGFB1 and TRP53 in intracellular Salmonella replication in pigs
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DOI: 10.1186/s13567-018-0616-9
Abstract: Peripheral blood transcriptome is an important intermediate data source for investigating the mechanism of Salmonella invasion, proliferation, and transmission. We challenged 4-week old piglets with Salmonella enterica serovar Typhimurium LT2 and investigated the peripheral blood… read more here.
Keywords: salmonella; salmonella replication; peripheral blood; expression ... See more keywords
Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages
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DOI: 10.7554/elife.90107
Abstract: Salmonella enterica serovar Typhimurium is a facultative intracellular pathogen that utilizes its type III secretion systems (T3SSs) to inject virulence factors into host cells and colonize the host. In turn, a subset of cytosolic immune… read more here.
Keywords: replication; within human; salmonella; salmonella replication ... See more keywords