Effect-Directed Synthesis of PhoP/PhoQ Inhibitors to Regulate Salmonella Virulence.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c01087
Abstract: Salmonella spp. are among the leading bacterial causes of foodborne infections. The PhoP/PhoQ two-component regulatory system serves as a master virulence regulator in Salmonella. Although PhoP/PhoQ represents an ideal target for disarming Salmonella virulence, it… read more here.
Keywords: phop phoq; salmonella virulence; directed synthesis; effect directed ... See more keywords
Salmonella virulence plasmid: pathogenesis and ecology.
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DOI: 10.1093/femspd/ftx070
Abstract: A current view on the role of the Salmonella virulence plasmid in the pathogenesis of animal and human hosts is discussed; including the possible relevance in secondary ecological niches. Various strategies towards further studies in… read more here.
Keywords: virulence plasmid; ecology; salmonella virulence; plasmid pathogenesis ... See more keywords
Methylation of PhoP by CheR Regulates Salmonella Virulence
Sign Up to like & getrecommendations! Published in 2021 at "mBio"
DOI: 10.1128/mbio.02099-21
Abstract: Posttranslational modifications (PTMs) play an important role in regulating enzyme activities, protein-protein interactions, or DNA-protein recognition and, consequently, modulate many biological functions. We demonstrated that PhoP, the response regulator of PhoP/PhoQ two-component system, could be… read more here.
Keywords: cher; salmonella virulence; phop; methylation phop ... See more keywords