Salpyran: A Cu(II) Selective Chelator with Therapeutic Potential.
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DOI: 10.1021/acs.inorgchem.1c01912
Abstract: We report the rational design of a tunable Cu(II) chelating scaffold, 2-(((2-((pyridin-2-ylmethyl)amino)ethyl)amino)methyl)phenol, Salpyran (HL). This tetradentate ligand is predicated to have suitable permeation, has an extremely high affinity for Cu compared to clioquinol (pCu7.4 =… read more here.
Keywords: salpyran selective; chelator; chelator therapeutic; therapeutic potential ... See more keywords