Impairment of mitochondrial oxidative phosphorylation in skin fibroblasts of SALS and FALS patients is rescued by in vitro treatment with ROS scavengers
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DOI: 10.1016/j.expneurol.2021.113620
Abstract: Amyotrophic lateral sclerosis (ALS) is a devastating, rapidly progressive, neurodegenerative disorder affecting upper and lower motor neurons. Approximately 10% of patients suffer from familial ALS (FALS) with mutations in different ubiquitously expressed genes including SOD1,… read more here.
Keywords: impairment mitochondrial; sals fals; mitochondrial oxidative; oxidative phosphorylation ... See more keywords