Mutation spectrum of amyotrophic lateral sclerosis in Central South China
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of aging"
DOI: 10.1016/j.neurobiolaging.2021.06.008
Abstract: To analyze the mutational spectrum of known ALS causative genes in China ALS patients. We comprehensively analyzed 51 ALS causative genes by combining different sequencing technologies in 753 unrelated ALS patients from Central South China.… read more here.
Keywords: south china; sals patients; spectrum; als patients ... See more keywords
Effect of the Minor C Allele of CNTN4 rs2619566 on Medial Hypothalamic Connectivity in Early-Stage Patients of Chinese Han Ancestry with Sporadic Amyotrophic Lateral Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s339456
Abstract: Objective Clinical symptoms such as major defects in energy metabolism may involve the hypothalamus in amyotrophic lateral sclerosis (ALS) patients. Our recent study discovered that the single-nucleotide polymorphisms (SNPs) of rs2619566, rs79609816 and rs10260404 are… read more here.
Keywords: connectivity; effect; sals patients; lateral sclerosis ... See more keywords