Improving hygroscopic stability of palmatine chloride by forming a pharmaceutical salt cocrystal of palmatine chloride-gallic acid with neutral molecule
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2021.102839
Abstract: Abstract In order to ameliorate the hygroscopicity of palmatine chloride (PMTCl), an unreported salt cocrystal (2(C21H22O4NCl)·C7H6O5·2CH3OH, PMTCl-GA) of palmatine chloride with gallic acid (GA) has been designed and synthesized by a solvent evaporation method. Structure… read more here.
Keywords: salt cocrystal; pmtcl; neutral molecule; palmatine chloride ... See more keywords
Photoreactive salt cocrystal: N+–H⋯N hydrogen bond and cation–π interactions support a cascade-like photodimerization of a 4-stilbazole
Sign Up to like & getrecommendations! Published in 2021 at "CrystEngComm"
DOI: 10.1039/d0ce01885f
Abstract: We describe hydrogen bonds (i.e., N+–H⋯N) in combination with cation⋯π interactions to enable a cascade-like [2 + 2] photodimerization of 4-stilbazole in a salt cocrystal. A four-component crystal assembly is composed of photoactive pyridinium ion… read more here.
Keywords: photodimerization; cascade like; like photodimerization; cation interactions ... See more keywords
A quantum crystallographic approach to short hydrogen bonds
Sign Up to like & getrecommendations! Published in 2021 at "Crystengcomm"
DOI: 10.1039/d1ce00355k
Abstract: In this work we use high-resolution synchrotron X-ray diffraction for electron density mapping, in conjunction with ab initio modelling, to study short O—H⋯O and O+—H⋯O− hydrogen bonds whose behaviour is known to be tuneable by… read more here.
Keywords: salt cocrystal; hydrogen; hydrogen bonds; cocrystal continuum ... See more keywords