A high salt diet aggravates retinal ischaemia/reperfusion injury.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2019.107784
Abstract: Ischaemia/reperfusion contributes to the pathophysiological process of many retinal diseases. Previous studies have shown that retinal ischaemia/reperfusion mainly results in neuronal degeneration, including thinning of the retina, death of retinal ganglion cells and reduction in… read more here.
Keywords: reperfusion; high salt; ischaemia reperfusion; salt diet ... See more keywords
RNA-seq analyses the effect of high-salt diet in hypertension.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.07.069
Abstract: OBJECTIVES High-salt diet is one of the major risk factors in the development of hypertension. Previous studies have observed a relationship between high-salt induced blood pressure levels and cardiac-cerebral disease. However, the molecular mechanism of… read more here.
Keywords: salt induced; induced hypertension; salt; salt diet ... See more keywords
High-salt diet aggravates pyelonephritis
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Nephrology"
DOI: 10.1038/s41581-020-0285-6
Abstract: Nature reviews | Nephrology Extracellular sodium is known to modulate immune cell function but the effects of a high-salt diet (HSD) on immunity might depend on organspecific responses to high dietary salt. The kidney response… read more here.
Keywords: hsd; salt; sodium; salt diet ... See more keywords
Effect of Salt Intake on Plasma and Urinary Uric Acid Levels in Chinese Adults: An Interventional Trial
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-20048-2
Abstract: Uric acid (UA) has been proposed as an important risk factor for cardiovascular and renal morbidity. We conducted an interventional trial to assess effects of altered salt intake on plasma and urine UA levels and… read more here.
Keywords: uric acid; plasma; salt intake; salt ... See more keywords
High-salt diet suppresses autoimmune demyelination by regulating the blood–brain barrier permeability
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2025944118
Abstract: Significance Dietary salt intake has been considered an important risk factor for autoimmune diseases like multiple sclerosis (MS). Here we studied the effects of a high-salt diet (HSD) using a spontaneous autoimmune disease mouse model… read more here.
Keywords: blood brain; salt; salt diet; brain barrier ... See more keywords
Long-term low salt diet increases blood pressure by activation of the renin-angiotensin and sympathetic nervous systems
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2018.1545850
Abstract: ABSTRACT Background The aim of this study was to investigate the effect of long-term low salt diet on blood pressure and its underlying mechanisms. Methods Male Sprague-Dawley (SD) rats were divided into normal salt diet… read more here.
Keywords: low salt; salt; blood pressure; salt diet ... See more keywords
Renal Protective Effects of N-Acetyl-Seryl-Aspartyl-Lysyl-Proline (Ac-SDKP) in Obese Rats on a High-Salt Diet
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Hypertension"
DOI: 10.1093/ajh/hpy052
Abstract: Abstract BACKGROUND Obesity is a public health problem, associated with salt sensitive hypertension, kidney inflammation, and fibrosis. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is a tetra peptide with anti-inflammatory and anti-fibrotic properties. However, its effect on preventing kidney damage… read more here.
Keywords: inflammation fibrosis; acetyl seryl; sdkp; salt diet ... See more keywords
A3964 Identification of chromosome 2 differentially expressed aortic genes linked to vascular inflammation using congenic rats fed a normal and high-salt diet
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548086.02252.5c
Abstract: Objectives: Chromosome 2 (Chr2) introgression from normotensive Brown Norway (BN) rats into hypertensive Dahl salt sensitive (SS) background (consomic SB2) reduced blood pressure (BP) and vascular inflammation under a normal-salt diet (NSD). BN Chr2 may… read more here.
Keywords: salt diet; hsd; vascular inflammation; rats fed ... See more keywords
GONADOECTOMY REDUCED THE DEGREE OF DEVELOPMENT OF RENOVASCULAR HYPERTENSION IN FEMALE RATS CAUSED BY STOP OF HIGH-SALT DIET
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000837696.64561.e4
Abstract: Objective: Excessive dietary salt intake is associated with an increased risk for hypertension. However, more research on measurement, storage and kinetics of sodium on blood pressure and sex hormones is required for dietary salt restrictions.… read more here.
Keywords: female rats; hypertension; high salt; salt diet ... See more keywords
Association of plasma cyclooxygenase-2 levels and genetic polymorphisms with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000002473
Abstract: OBJECTIVE Cyclooxygenase (COX)-2, an inducible isoform of the major rate-limiting enzymes that regulate the production of prostaglandins is associated with injury, inflammation and proliferation. We sought to examine whether plasma COX-2 levels and its genetic… read more here.
Keywords: cox; salt; hypertension; salt sensitivity ... See more keywords
Cardiorenai protective effects of sodium-glucose cotransporter 2 inhibition in combination with angiotensin II type 1 receptor blockade in salt-sensitive Dahl rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000003099
Abstract: Objective: The kidney plays a central role in regulating the salt sensitivity of blood pressure (BP) by governing sodium excretion and reabsorption via renal sodium transporters. We hypothesized that sodium-glucose cotransporter 2 (SGLT2) inhibition and… read more here.
Keywords: angiotensin; inhibition; combination; cotransporter ... See more keywords