Synthesis, antitubercular evaluation, and molecular docking studies of hybrid pyridinium salts derived from isoniazid
Sign Up to like & getrecommendations! Published in 2023 at "Drug Development Research"
DOI: 10.1002/ddr.22039
Abstract: In the quest to develop potent inhibitors for Mycobacterium tuberculosis, novel isoniazid‐based pyridinium salts were designed, synthesized, and tested for their antimycobacterial activities against the H37Rv strain of Mycobacterium tuberculosis using rifampicin as a standard.… read more here.
Keywords: derived isoniazid; synthesis antitubercular; pyridinium salts; antitubercular evaluation ... See more keywords
A novel quaternary ammonium salts derived from α-amino acids with large steric hindrance group and its application in asymmetric Mannich reaction
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.131484
Abstract: Abstract Quaternary ammonium salts derived from amino acids with large steric hindrance group have been designed and synthesized, which promoted the asymmetric Mannich reaction of glycine imines with N-Boc-aldimines in excellent yields with high enantio-… read more here.
Keywords: ammonium salts; amino acids; salts derived; group ... See more keywords