Platinum salts in the treatment of BRCA-associated breast cancer: A true targeted chemotherapy?
Sign Up to like & getrecommendations! Published in 2019 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2019.01.016
Abstract: Germline pathogenic mutations in breast cancer (BC) susceptibility genes (gBRCA1/2) are the most frequent inherited alterations in BC and are involved in the homologous recombination pathway, the principal mechanism of DNA double strand break repair.… read more here.
Keywords: platinum; platinum salts; breast cancer; brca ... See more keywords