Pediatric glioblastoma cells are sensitive to drugs that inhibit eIF2α dephosphorylation and its phosphomimetic S51D variant
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DOI: 10.3389/fonc.2022.959133
Abstract: We found that pediatric glioblastoma (PED-GBM) cell lines from diffuse intrinsic pontine glioma (DIPG) carrying the H3K27M mutation or from diffuse hemispheric glioma expressing the H3G34R mutation are sensitive to the combination of vorinostat (a… read more here.
Keywords: ped gbm; eif2 dephosphorylation; parp inhibitors; salubrinal raphin ... See more keywords