Salusin-β mediate neuroprotective effects for Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.07.059
Abstract: Neuropeptides, small peptides found in many mammalian brain, play key roles in communicating with each other to modulate neuronal activity. Here, we reported that endogenous neuropeptide salusin-β has neuroprotective effects on the midbrain dopamine neurons… read more here.
Keywords: midbrain dopamine; salusin; neuroprotective effects; parkinson disease ... See more keywords
Identification and quantification of plasma free salusin-β, an endogenous parasympathomimetic peptide
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-08288-0
Abstract: Salusin-β is an endogenous parasympathomimetic proatherosclerotic peptide. Salusin-β was initially predicted from bioinformatic analyses and later immunologically detected in human biofluids. However, elucidation of salusin-β bioactivity has faced enormous challenges because of its unique physicochemical… read more here.
Keywords: endogenous parasympathomimetic; peptide; salusin; plasma free ... See more keywords
Assessment of salusin alpha and salusin beta levels in patients with newly diagnosed dipper and non-dipper hypertension
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2020.1797086
Abstract: ABSTRACT Objective The pathophysiology of non-dipper hypertension has not been clarified. The relationship between salusins with atherosclerosis and hypertension has gained attention in recent years. The aim of this paper is to investigate whether salusins… read more here.
Keywords: newly diagnosed; salusin; dipper hypertension; blood pressure ... See more keywords
Novel risk factor for fatal arrhythmia in Brugada syndrome
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.0735
Abstract: Brugada syndrome (BrS) is a genetic disease associated with increased risk of ventricular fibrillation (VF)/ventricular tachycardia (VT). The VF/VT in BrS occurs more frequently during a night time or at a rest with parasympathetic nerve… read more here.
Keywords: brs; risk; salusin; brugada syndrome ... See more keywords
Overexpression of Salusin-α Inhibits Vascular Intimal Hyperplasia in an Atherosclerotic Rabbit Model
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/8973986
Abstract: Inhibiting vascular endothelial foam is the focus of clinical attention. Using SonoVue (an ultrasound contrast agent), the salusin-α gene was transfected into the arterial intima of an atherosclerotic rabbit model induced by a high-fat diet… read more here.
Keywords: salusin; atherosclerotic rabbit; group; salusin gene ... See more keywords
Relationship of salusin-alpha and salusin-beta levels with atherosclerosis in patients undergoing haemodialysis.
Sign Up to like & getrecommendations! Published in 2019 at "Singapore medical journal"
DOI: 10.11622/smedj.2018123
Abstract: INTRODUCTION In patients undergoing haemodialysis, cardiovascular mortality and morbidity, characterised by accelerated atherosclerosis and increased inflammation, are elevated. Salusins are newly defined molecules in the atherosclerotic processes, and while salusin-alpha (Sal-α) acts as an antiatherogenic… read more here.
Keywords: salusin; sal; healthy controls; patients undergoing ... See more keywords
The effect of salusin-β on expression of pro- and anti-inflammatory cytokines in human umbilical vein endothelial cells (HUVECs)
Sign Up to like & getrecommendations! Published in 2018 at "ARYA Atherosclerosis"
DOI: 10.22122/arya.v14i1.1602
Abstract: BACKGROUND Atherosclerosis is one of the predominant causes of cardiovascular disease (CVD). Several studies indicated the significant pathophysiological role of salusin-β in atherosclerosis. Cytokines are involved in all stages of atherosclerosis. Therefore, we aimed to… read more here.
Keywords: inflammatory cytokines; expression; salusin; effect salusin ... See more keywords