Salvage Chemoimmunotherapy With Inotuzumab Ozogamicin Combined With Mini–Hyper-CVD for Patients With Relapsed or Refractory Philadelphia Chromosome–Negative Acute Lymphoblastic Leukemia: A Phase 2 Clinical Trial
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.2380
Abstract: Importance The outcome of patients with relapsed or refractory (R/R) acute lymphoblastic leukemia (ALL) is poor. Inotuzumab ozogamicin, a CD22 monoclonal antibody bound to calicheamicin, has single-agent activity in R/R ALL. Objective To evaluate the… read more here.
Keywords: relapsed refractory; inotuzumab; salvage; acute lymphoblastic ... See more keywords
Decipher test impacts decision making among patients considering adjuvant and salvage treatment after radical prostatectomy: Interim results from the Multicenter Prospective PRO‐IMPACT study
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DOI: 10.1002/cncr.30665
Abstract: Patients with prostate cancer and their providers face uncertainty as they consider adjuvant radiotherapy (ART) or salvage radiotherapy (SRT) after undergoing radical prostatectomy. The authors prospectively evaluated the impact of the Decipher test, which predicts… read more here.
Keywords: prostatectomy; impact; salvage; decision making ... See more keywords
NAD+ salvage governs mitochondrial metabolism invigorating NK cell anti-tumor immunity.
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32658
Abstract: BACKGROUND & AIMS Natural killer (NK) cells are key players in tumor immunosurveillance and metabolic adaption manipulates their fate and functional state. The nicotinamide adenine dinucleotide (NAD+ ) has emerged as a vital factor to… read more here.
Keywords: salvage; cell; metabolism; anti tumor ... See more keywords
Regional pedicled flap salvage options for large head and neck defects: The old, the new, and the forgotten
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DOI: 10.1002/lio2.983
Abstract: The objective of this article is to review options for regional pedicled reconstruction for large head and neck defects in a salvage setting. read more here.
Keywords: salvage; head neck; large head; neck defects ... See more keywords
Soft tissue reconstruction and salvage of infected fixation hardware in lower extremity trauma
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DOI: 10.1002/micr.30176
Abstract: Tibial fracture management may be complicated by infection of internal fixation hardware (iIFH) resulting in increased morbidity and amputation rate. When iIFH removal is not possible, salvage of the lower extremity is attempted through debridement,… read more here.
Keywords: lower extremity; salvage; soft tissue; fixation hardware ... See more keywords
Surgical and demographic predictors of free flap salvage after takeback: A systematic review
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DOI: 10.1002/micr.30921
Abstract: Microsurgical free tissue transfer (FTT) is a widely employed surgical modality utilized for reconstruction of a broad range of defects, including head and neck, extremity, and breast. Flap survival is reported to be 90%–95%. When… read more here.
Keywords: salvage; demographic predictors; surgical demographic; systematic review ... See more keywords
High-dose-rate brachytherapy as salvage modality for locally recurrent prostate cancer after definitive radiotherapy
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DOI: 10.1007/s00066-017-1157-2
Abstract: PurposeTo review the current status of interstitial high-dose-rate brachytherapy as a salvage modality (sHDR BRT) for locally recurrent prostate cancer after definitive radiotherapy (RT).Materials and methodsA literature search was performed in PubMed using “high-dose-rate, brachytherapy, prostate… read more here.
Keywords: high dose; salvage; prostate cancer; dose rate ... See more keywords
Re-exploration in the early postoperative period has a better salvage rate in free flaps
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DOI: 10.1007/s00238-020-01744-7
Abstract: The most significant complication of free flap reconstruction is flap failure, which can be a result of numerous factors but ultimately affecting the vascularity of the flap tissues. In cases of doubtful flap viability re-exploration… read more here.
Keywords: exploration; postoperative period; salvage; salvage rate ... See more keywords
Surgeons’ Dilemma: Treatment of Implant-Associated Infection in the Cosmetic Breast Augmentation Patient
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DOI: 10.1007/s00266-019-01369-7
Abstract: BackgroundAugmentation mammaplasty is the most common plastic surgical procedure performed in the USA. The management of severe implant-associated infection is a challenge, and the traditional two-stage treatment is associated with significant limitations. The aim of… read more here.
Keywords: breast augmentation; treatment; infection; salvage ... See more keywords
Between a rux and a hard place: evaluating salvage treatment and outcomes in myelofibrosis after ruxolitinib discontinuation
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DOI: 10.1007/s00277-017-3194-4
Abstract: Ruxolitinib is a JAK1/2 inhibitor that is effective in managing symptoms and splenomegaly related to myelofibrosis (MF). Unfortunately, many patients must discontinue ruxolitinib, at which time treatment options are not well defined. In this study,… read more here.
Keywords: salvage treatment; treatment; salvage; ruxolitinib discontinuation ... See more keywords
The role of PSMA PET scans in salvage therapy planning
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DOI: 10.1007/s00345-017-2149-7
Abstract: Biochemical recurrence after radical therapy for prostate cancer can occur. Prostate-specific membrane antigen (PSMA) positron emission tomography-computed tomography (PET-CT) imaging is increasingly used in salvage therapy. It is also used to triage those who will… read more here.
Keywords: pet; therapy; pet imaging; psma pet ... See more keywords