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   Articles with "salvia miltiorrhiza" as a keyword



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Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B.

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recommendations! Published in 2017 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2017.10.013

Abstract: Protein tyrosine phosphatase 1B (PTP1B) is a negative regulator that plays an important role in many signaling pathways, especially those associated with insulin resistance. In this study, we investigated the anti-diabetic potential of 12 natural… read more here.

Keywords: natural tanshinones; salvia miltiorrhiza; tyrosine phosphatase; protein tyrosine ... See more keywords
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In vitro inhibitory effects of components from Salvia miltiorrhiza on catalytic activity of three human AA ω-hydroxylases.

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recommendations! Published in 2021 at "Drug metabolism and pharmacokinetics"

DOI: 10.1016/j.dmpk.2021.100402

Abstract: CYP4 enzymes are involved in the metabolism of xenobiotics and endogenous molecules. 20-Hydroxyeicosatetraenoic acid (20-HETE), the arachidonic acid (AA) ω-hydroxylation metabolite catalyzed by CYP4A/4F enzymes, is implicated in various biological functions. The goal of this… read more here.

Keywords: components salvia; effects components; cyp4f2 cyp4f3b; inhibitory effects ... See more keywords
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Synergistic use of florfenicol and Salvia miltiorrhiza polysaccharide can enhance immune responses in broilers.

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recommendations! Published in 2021 at "Ecotoxicology and environmental safety"

DOI: 10.1016/j.ecoenv.2020.111825

Abstract: To explore the effect of florfenicol (FFC) combined with Salvia miltiorrhiza polysaccharide (SMPs) on immune function of Broilers. One hundred and twenty-one-day-old chicks were chosen and divided into 6 groups. The group A received standard… read more here.

Keywords: synergistic use; enhance immune; basal diet; salvia miltiorrhiza ... See more keywords
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Salvia miltiorrhiza polysaccharides alleviates florfenicol induced kidney injury in chicks via inhibiting oxidative stress and apoptosis.

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recommendations! Published in 2022 at "Ecotoxicology and environmental safety"

DOI: 10.1016/j.ecoenv.2022.113339

Abstract: Florfenicol (FFC) is a commonly used antibiotic in animal husbandry, which is easy to cause organs damage in a variety of animals. It has been proved to have nephrotoxicity and affect the yield and quality… read more here.

Keywords: injury; apoptosis; polysaccharides alleviates; miltiorrhiza polysaccharides ... See more keywords
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New depsides from the roots of Salvia miltiorrhiza and their radical-scavenging capacity and protective effects against H2O2-induced H9c2 cells.

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recommendations! Published in 2017 at "Fitoterapia"

DOI: 10.1016/j.fitote.2017.06.018

Abstract: Phytochemical investigation of the roots of Salvia miltiorrhiza led to isolations of two new depsides (1-2), along with thirteen known compounds (3-15). Their structures and relative stereochemistry were elucidated by NMR spectral (1H and 13C… read more here.

Keywords: scavenging capacity; roots salvia; radical scavenging; new depsides ... See more keywords
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Salchaetoglobosins A and B: Cytochalasan alkaloids from Chaetomium globosum D38, a fungus derived from Salvia miltiorrhiza.

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recommendations! Published in 2021 at "Fitoterapia"

DOI: 10.1016/j.fitote.2021.104874

Abstract: Chemical investigation on the solid rice culture of Chaetomium globosum D38, an endophytic fungus derived from Salvia miltiorrhiza, has afforded two new 19,20-seco-chaetoglobosins, salchaetoglobosins A (1) and B (2), along with three known analogues, chaetoglobosins… read more here.

Keywords: derived salvia; globosum d38; fungus derived; salvia miltiorrhiza ... See more keywords
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Diverse responses of tanshinone biosynthesis to biotic and abiotic elicitors in hairy root cultures of Salvia miltiorrhiza and Salvia castanea Diels f. tomentosa.

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recommendations! Published in 2018 at "Gene"

DOI: 10.1016/j.gene.2017.11.067

Abstract: Salvia miltiorrhiza (S. miltiorrhiza) and Salvia castanea Diels f. tomentosa (S. castanea) are both used for treatment of cardiovascular diseases. They have the same bioactive compound tanshinones, but whose contents are hugely different. This study… read more here.

Keywords: miltiorrhiza salvia; castanea; salvia miltiorrhiza; tanshinone biosynthesis ... See more keywords
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SmbHLH53 Is Relevant to Jasmonate Signaling and Plays Dual Roles in Regulating the Genes for Enzymes in the Pathway for Salvianolic Acid B Biosynthesis in Salvia miltiorrhiza.

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recommendations! Published in 2020 at "Gene"

DOI: 10.1016/j.gene.2020.144920

Abstract: Basic helix-loop-helix (bHLH) transcription factors play essential roles in myriad regulatory processes, including secondary metabolism. In this study with Salvia miltiorrhiza, we isolated and characterized SmbHLH53, which encodes a bHLH family member. Expression of this… read more here.

Keywords: genes enzymes; salvianolic acid; enzymes pathway; salvia miltiorrhiza ... See more keywords
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Effect of Salvia miltiorrhiza on acetylcholinesterase: Enzyme kinetics and interaction mechanism merging with molecular docking analysis.

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recommendations! Published in 2019 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2019.05.132

Abstract: Acetylcholinesterase (AchE) serves as an important target for Alzheimer's disease. Salvia miltiorrhiza has been used to treat cardiovascular disease for hundreds of years. However, the interaction between S. miltiorrhiza and AchE is still inadequate. Herein,… read more here.

Keywords: ache; acetylcholinesterase; interaction; salvia miltiorrhiza ... See more keywords
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Integrative analysis of metabolome and transcriptome reveals the mechanism of color formation in white root (Salvia miltiorrhiza)

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recommendations! Published in 2021 at "Industrial Crops and Products"

DOI: 10.1016/j.indcrop.2021.113784

Abstract: Abstract Tanshinones are a class of bioactive components and pigments found in the traditional Chinese herb Salvia miltiorrhiza (S. miltiorrhiza). To clarify the biosynthesis of tanshinones in S. miltiorrhiza roots, the metabolome and transcriptome were… read more here.

Keywords: miltiorrhiza; root; metabolome transcriptome; white root ... See more keywords
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A network pharmacology approach to investigate the anti-inflammatory mechanism of effective ingredients from Salvia miltiorrhiza.

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recommendations! Published in 2019 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2019.106040

Abstract: Salvia miltiorrhiza, known as Danshen in Chinese, has been widely used to treat cardiovascular diseases in China. Tanshinone I (Tan I) and cryptotanshinone (CST) are the lipid-soluble and effective components from Salvia miltiorrhiza. However, the… read more here.

Keywords: network; inflammation; pharmacology; salvia miltiorrhiza ... See more keywords