Articles with "salvinorin" as a keyword



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Statistical comparison of mass spectra of salvinorins in Salvia divinorum and related Salvia species

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Published in 2020 at "Forensic Chemistry"

DOI: 10.1016/j.forc.2019.100192

Abstract: Abstract In many forensic science disciplines, mass spectrometry is used for the analysis and comparison of case samples to reference materials. To increase confidence in identifications made from such comparisons, our laboratory previously developed a… read more here.

Keywords: salvinorin; mass spectra; mass; divinorum ... See more keywords
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A unique natural selective kappa-opioid receptor agonist, salvinorin A, and its roles in human therapeutics.

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Published in 2017 at "Phytochemistry"

DOI: 10.1016/j.phytochem.2017.02.001

Abstract: Until the mid-60s, only the Mazatecs, an indigenous group from Oaxaca, Mexico, used Salvia Divinorum (S. divinorum) due to its hallucinogen properties. Later it was found that the hallucinogen effects of this plant were caused… read more here.

Keywords: agonist; salvinorin; opioid receptor; kappa opioid ... See more keywords
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Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ-OR Agonist

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Published in 2017 at "ACS Central Science"

DOI: 10.1021/acscentsci.7b00488

Abstract: Salvinorin A (SalA) is a plant metabolite that agonizes the human kappa-opioid receptor (κ-OR) with high affinity and high selectivity over mu- and delta-opioid receptors. Its therapeutic potential has stimulated extensive semisynthetic studies and total… read more here.

Keywords: salvinorin; strategic bond; step synthesis; dynamic strategic ... See more keywords
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DARK Classics in Chemical Neuroscience: Salvinorin A.

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Published in 2020 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.0c00608

Abstract: Salvinorin A is the main bioactive compound in Salvia divinorum, an endemic plant with ancestral use by the inhabitants of the Mazateca mountain range (Sierra Mazateca) in Oaxaca, México. The main use of la pastora,… read more here.

Keywords: salvinorin; dark classics; chemical neuroscience; chemistry ... See more keywords
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Cutting-Edge Search for Safer Opioid Pain Relief: Retrospective Review of Salvinorin A and Its Analogs

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Published in 2019 at "Frontiers in Psychiatry"

DOI: 10.3389/fpsyt.2019.00157

Abstract: Over the years, pain has contributed to low life quality, poor health, and economic loss. Opioids are very effective analgesic drugs for treating mild, moderate, or severe pain. Therapeutic application of opioids has been limited… read more here.

Keywords: salvinorin analogs; salvinorin; search; cutting edge ... See more keywords